At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$133,500 - $217,800

At Lilly, we serve an extraordinary purpose. For more than 140 years, we have worked tirelessly to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world’s greatest health challenges

Responsibilities:

This analytical position is in an early phase chemistry development and scale-up laboratory and entails developing analytical methods and analyzing for identity, potency and purity of starting materials, reaction conversions, work-up efficiency, crystallization productivity and endpoints, the purity, potency, polymorphism (API), and particle size (API) of isolated products, and overall mass balance tie up. The analyst is responsible for operating and maintaining analytical equipment in a pharmaceutical research and development laboratory. The analyst will be involved in receiving analytical methods from early phase process chemistry and medicinal chemistry labs and will be responsible for: receiving and establishing reference materials, evaluating the suitability of incoming analytical methods and modifying or developing new methods as needed, analyzing scale-up reactions to support early phase development and for demonstrations towards technical transfers to a GMP kilo-lab. In collaborations, the analyst will engage in reaction development by performing reaction characterization research to identify impurities and amounts and rates of formation to better understand competing mechanistic pathways. Understanding the stability of process streams and isolated materials will also be part of the analyst’s responsibility.

Basic Qualification

MS/PhD level analytical chemist with experience developing methods and analyzing reactions and materials to support pharmaceutical process development.

Additional Preferences:

Expected to maintain a safe, clean, well-organized, and productive lab space.Experience with the development and use of a variety of analytical methods: HPLC/UPLC, GC, MS, NMR, KF, TGA, DSC, XRD, ICP etc. Process analysis and quantification, tying up mass balance, and material characterization.Familiarity with crystallization and physical/solid state characterization: experience with crystallization monitoring/analysis to understand kinetics and endpoints. Also expected to analyze for polymorphism and particle size and other solid-state characteristics in collaboration with partner analysts.Proficiency with the purification of chemicals via chromatography is a plus.Maintaining a well-organized and detailed lab notebook with accurate descriptions of method development and observations to enable the preparation of technical packages/technical transfers and accurate replication in receiving labs.Participate in training, mentoring, and supporting analytical chemists and chemists in the development and use of analytical methods for pharmaceutical process development.  Analytical testing plans - Developing an analytical testing plan to ensure that all facets of a chemical process are understood and under control. This entails characterization of starting materials towards specification setting, establishing reaction end points, determining unit operation end points and optimal amounts of chemicals to use for reactions, work-ups/extractions, crystallizations, washes, etc.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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