Site Name: UK - Hertfordshire - Stevenage Posted Date: Nov 7 2024 At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together. Find out more: Our approach to R&D. We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme. We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work. Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK Associate Director, Tumour Tissue Multi-omics (m/f/d) We are seeking a highly motivated scientist with experience in oncology to join the Oncology Translational Research team in GSK Oncology. The successful candidate will work as part of a broad team that applies translational model systems through both internal and external partnerships to enable cancer patient risk stratification, identify biomarkers and predict future targeted and/or immuno-therapy susceptibilities. Key responsibilities: Represent OTRO in discussions with clinical asset teams regarding translational studies and tissue profiling, delivered via the OTRO lab teams, for translational work to address key asset team questions. Lead and manage a team to deliver the patient derived explant (PDE) multiomics capabilities, including evaluation of internal and external options to increase robustness, scale and throughput. Oversee all technical aspects of development, assay validation and experimental implementation of the selected approaches. Work in partnership with the OTRO external engagement team to identify and implement improved access to fresh tumour tissues through biobanks, CROs and partnerships. Demonstrate exceptional interpersonal skills to build relationships with internal Oncology Translational Research teams and with cross-functional partners in disciplines (such as AI/ML, Precision Medicine, Oncology Project Leaders, Oncology Research Units and Oncology Clinical Development etc) to lead the conduct of translational studies and improve mechanistic understanding of our assets. Must be able to manage multiple projects and workstreams, including planning of workload, resourcing requirements and risk management to deliver the team’s objectives on time. Manage data integrity and ensure compliance with industry standards. Report to and partner with the Executive Director to deliver the strategy for the patient derived explant team. Requirements: Ph.D. or equivalent experience in a relevant scientific discipline (eg. oncology, immuno-oncology) Proven experience in leading and executing research projects, with the ability to work effectively both independently and as part of a multidisciplinary matrix team. Extensive experience in the use of non-clinical translational experimental approaches to address key mechanistic questions. Prior exposure to industry drug discovery and development and prior experience with ADCs or TCEs would be advantageous. Demonstrates flexibility and ability to work well with ambiguity and in intense situations Proactive, ‘can-do’ mindset that bridges ideas to realizable and deliverable solutions to solve problems The candidate will need to be highly organised with good attention to detail Exceptional oral and written communication, influencing and interpersonal skills Sense of urgency, flexibility, integrity and accountability. Closing Date for Applications – 22 November 2024 Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. #LI-GSK Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. 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