Associate Scientist, Downstream Process Development - Contract - Gaithersburg, MD

Proclinical is seeking an Associate Scientist to join a dedicated Downstream Process Development team.

Primary Responsibilities:

This role will focus on developing, scaling up, and providing technical support for cGMP manufacturing of protein-based vaccines. The successful candidate will ensure the creation of scientifically sound and scalable purification processes and generate materials for developmental studies.

Skills & Requirements:

Relevant scientific discipline (MS or BS) with hands-on downstream purification experience.Proven history in purification of biologics and experience in chromatography methods and TFF unit operations is a plus.Ability to perform multiple functions in a fast-paced environment.Excellent record keeping skills is a necessity in order to adequately record, analyze and document data.Good organization skills.Demonstrated scientific and technical communication skills, both verbal and written.Proficiency in Window based software including Excel, PowerPoint and Word.Must be a highly self-motivated, organized, and productive individual.

The Associate Scientist's responsibilities will be:

Support the development of purification processes by reviewing and compiling relevant literature data.Perform scale-up of processes to deliver materials for pre-clinical and clinical studies.Execute optimization experiments to ensure robust, high-purity, and scalable processes for clinical stage manufacturing.Design experimental work under the supervision of senior scientists.Process complex data and clearly communicate the implications of the results.Generate, manage, evaluate, and maintain critical data in an organized manner and provide assessment reports.Provide reagents and other supplies for various projects and departments.Support process characterization studies, process validation, and tech transfer processes as needed.Maintain inventory of lab supplies and order lab consumables as needed.Prepare buffers and pack columns at different scales.Test in-process samples using methods such as SDS-PAGE, Western blot, A280 (Nanodrop), BCA, DNA, and host cell protein ELISA assays.Operate glass washing instruments and autoclaves as needed.Engage hands-on in laboratory and scale-up operations.

If you are having difficulty in applying or if you have any questions, please contact Jackie Cerchio at j.cerchio@proclinical.com.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

INDSCIC