Great opportunity to get your foot in the door with one of the top Biotech companies in the Cambridge, MA area!

Must have experienced with any of the following python models: pandas, numpy, scanpy, anndata, scikit-learn. Being familiar with: pytorch or keras, scvi-tools or scarches

If interested, please reach out directly to Lindsee Allienello at lallienello @ actalentservices.com

Description:

Systems Immunology and Immune Profiling center SI/IPC team in Cambridge Massachusetts is seeking a highly skilled contractor with expertise in bioinformatics and computational biology with a strong emphasis on proteomics analysis including Cytometry by Time Of Flight CyTOF Imaging Mass Cytometry IMC and Mass Spectrometry MS. The successful candidate will play a critical role in analyzing internal datasets and advancing our mission to identify novel therapeutic targets for autoimmune and chronic inflammatory diseases.

Key Responsibilities:

Perform advanced analysis of high-dimensional proteomics data including CyTOF Flow Cytometry and MS to generate actionable insights into disease mechanisms. Help develop and optimize computational workflows and pipelines for processing analyzing and interpreting proteomics datasets. Perform image-based quantification of proteins using IMC focusing on spatial distribution and co-localization of immune cells and other tissue components in situ. Collaborate with multidisciplinary teams including immunologists data scientists and biologists to interpret proteomics data and translate findings into preclinical and clinical research applications. Present complex analytical approaches and results to both technical and non-technical stakeholders effectively communicating the scientific rationale and implications.

Skills and Qualifications:

M.S. in bioinformatics computational biology proteomics biochemistry or a related field. Proficiency in programming languages such as R and Python and experience working in Unix/Linux environments. Being experienced with pandas, numpy, scanpy, anndata, scikit-learnBeing familiar with: pytorch or keras, scvi-tools or scarches Knowledge of statistical methods and machine learning techniques applicable to the analysis of large-scale proteomics datasets.

Preferred Skills:

Experience with computational methods for protein quantification identification of post-translational modifications and protein-protein interaction network analysis. Familiarity with CyTOF spatial CyTOF IMC and Flow Cytometry data analysis techniques is desirable. Expertise in proteomics data analysis including Mass Spectrometry MS-based proteomics and familiarity with related software tools or other proteomics data analysis platforms. Strong communication skills with the ability to present complex data to both scientific and non-scientific audiences. A proactive and collaborative approach to problem-solving in a dynamic fast-paced research environment. Ability to manage multiple projects simultaneously and adapt to changing priorities. Contribute to the preparation of scientific publications presentations for conferences and regulatory submissions if any.

Key Competencies:

Demonstrated ability to work independently while contributing effectively to multidisciplinary teams. Organizational skills with the capacity to manage competing priorities and deliver high-quality work within deadlines. Commitment to continuous learning innovation and staying current with the latest developments in proteomics and computational biology.

Experience Level:

Intermediate Level

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.

Diversity, Equity & Inclusion

At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:

Hiring diverse talent Maintaining an inclusive environment through persistent self-reflection Building a culture of care, engagement, and recognition with clear outcomes Ensuring growth opportunities for our people

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email actalentaccommodation@actalentservices.com for other accommodation options.