Bioinformatics Research Scientist
St. Jude Children's Research Hospital
A Bioinformatics Research Scientist position is immediately available under the supervision of Dr. Zhaoming Wang in the Department of Epidemiology and Cancer Control at St. Jude Children’s Research Hospital. Wang Lab is seeking a talented and highly motivated data scientist to apply established and innovative approaches towards analyzing multi-omics data to discover potential biomarkers for risk of chronic health conditions including second cancers among long-term survivors of childhood cancer. In addition to large-scale molecular profiling data encompassing genome, epigenome, and transcriptome, we also have access to rich longitudinal clinical data from the two largest cohorts of childhood cancer survivors: St. Jude Lifetime Cohort and Childhood Cancer Survivor Study. Strong expertise in R and/or Python programming is required. Extensive working experience in next-generation sequencing analysis and domain knowledge in one or more of bioinformatics, biostatistics and genetic/molecular epidemiology are highly desired. The ability to work independently and in a team-setting (multi-tasking and effective communications) is also essential. The Wang Lab is currently focused on cancer genetics (pediatric cancers, subsequent adult cancers), aging biomarkers (telomere, epigenetic age, clonal hematopoiesis), and multi-omics integrative analysis (including single-cell approaches). Job Responsibilities: Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and oversee quality check. Design and prepare materials and courses for training on various bioinformatics software and databases, computing, data mining, and analysis. Act as a liaison between end-users, software developers, system designers, and different departments. Establish protocols or best practices for common research tasks and SOP, evaluate products and solutions to make recommendations, and integrate solutions. Lead the development, implementation, installation, and maintenance of databases; coordinate data collection, database implementation, and usage and any hardware and software related to database collection. Develop programs to assist in the analysis of data within the databases. Assist in planning, coordinating, and organizing projects across departments and delegate tasks based on priority, expertise, and capacity. Perform other duties as assigned to meet the goals and objectives of the department and institution. Maintains regular and predictable attendance. Work closely with Dr. Wang and others with the overarching goal of contributing to the clinical research by melding multi-omics data with clinical/phenotypic data for discoveries in the area of precision preventive medicine for survivorship care. Contribute to multi-omics data management and primary sequencing data analysis by setting up/improving automation pipeline with established computational methods. Lead the development of analytical workflows (secondary analyses) for assigned research projects. Learn new bioinformatics techniques for data mining in molecular phenotyping (e.g., deconvolution analysis, mosaicism detection, HLA imputation) Contribute to the preparation and submission of manuscripts for publication. Present to collaborators and team members to report scientific discoveries and educate researchers about relevant methods, software or scientific results. Perform other duties as assigned to meet the goals and objectives of the department and institution. Minimum Education and/or Training: Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. Master's degree or PhD preferred. Minimum Experience: Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience. Experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
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