Precise Systems, Inc. is seeking a Ph.D. Biomanufacturing Senior Scientist with advanced experiences in fermentation, downstream processing, biochemical, biomaterial, distillation, liquid-liquid extraction, chromatography, chemistry, biology, and/or other chemical and biological engineering processing techniques to lead biomanufacturing projects as part of an established team. We seek candidates with well-demonstrated record in the process development, production, and characterization of molecule manufacturing from small molecule biochemicals to solid biomaterial products. Experience with operation of pilot-scale chemical processing equipment, translation of bench methods to pilot scale systems, and analytical chemistry data analysis and interpretation is a plus.
The candidate will be supporting efforts with heavy emphasis on pilot-scale biochemical recovery from fermentation broth as part of a pipeline development team who makes kilogram-scale volumes of various biochemicals and biomaterials for prototyping efforts. Therefore, applicants with a willingness and desire to work collaboratively with teammates while demonstrating personal competency and meaningful creative and technical leadership with be highly favored.
Duties:
• Lead development of project-specific process improvements in the Biochemical DSP space
• Collaboratively develop workflows to translate bench-scale downstream processes to pilot-scale operations
• Set up and execute workflows in the Biochemical DSP lab while adhering to all regulations
• Sample systems as appropriate/record process data & report on analysis of data
• Active participant in regular process development conversations with teammates and project collaborators
• Regularly share project data with teammates and collaborators to advance joint project efforts
• Participate in Tech Transfer conversations with potential collaborators (entering and exiting facility)
• Keep detailed records of laboratory operations, all process-related developments, and compile data into regular technical reports
• Update and maintain SOP documentation in the Biochemical DSP space IAW all regulations
• Maintain record logs of all operational activities IAW all regulations
• Report process developments in Invention Disclosures towards Patent Applications as appropriate
Required Experience:
• Eligible to obtain and maintain a security clearance.
• PhD in Chemical Engineering, Biochemical Engineering, Chemistry, or Biology or related field preferred but others will be considered depending on qualifications.
• Demonstrated hands-on experience in chemical processing techniques such as distillation, liquid-liquid-extraction, and/or pilot-scale fermentation.
• Understanding of organic/solvent chemical processing and the various materials and techniques is essential.
• Understand the economics of biomanufacturing and scale-up considerations.
• Must be able to design, plan, and execute experiments in order to understand the behavior of biomanufactured solid biomaterials and liquid biochemical small molecules.
• Demonstrated technical / scientific leadership skills and a passion for problem solving.
• Excellent oral and written communication skills.
• Able to work productively and independently in an interdisciplinary team environment.
Desired Experience:
• Experience with both microbial fermentation and biomaterial extraction.
• Familiarity with tools and mechanical devices, hands-on projects, willingness to turn a wrench as needed.
• Comfortable at heights and willing to climb ladders as needed.
• Creativity in identifying places where application of available novel biomaterials could solve relevant problems.