US: Loxo Louisville CO, United States of America
15 hours ago
Chemist - Early Phase Process Chemistry

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$69,000 - $179,300

At Lilly, we serve an extraordinary purpose. For more than 140 years, we have worked tirelessly to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world’s greatest health challenges

Responsibilities:

In this role, the Chemist would be operating and maintaining chemistry scale-up equipment in a pharmaceutical research and development laboratory. Actively involved in receiving chemistry from early phase process chemistry and medicinal chemistry labs: evaluating the safety of the incoming procedures in collaboration with the safety group, ordering and staging chemicals, obtaining reference materials and participating in setting up analytical methods, performing scale-up reactions to supply materials to support early phase development and to complete demonstrations towards technical transfers to a GMP kilo-lab. Training and assisting scientists that submit chemistry for scale-up and demonstrations. Participation in the development of chemical reactions, work-ups, and purifications/isolations.

Basic Qualification

BS/MS level chemist with experience developing and scaling reactions from gram to hundreds of grams scale.

Additional Preferences:

Expected to maintain a safe, clean, well-organized, and productive chemistry lab.Good working knowledge of organic chemistry and mechanisms and application to reaction improvement and optimization.Experience with a variety of analytical techniques: HPLC/UPLC, MS, NMR, GC, KF, DSC, XRD, etc. Process quantification and tying up mass balance.Familiarity with physical/solid state chemistry: crystallization development and optimization, understanding of polymorphism and particle size control, and safe handling of solids/dry end processing.Proficiency with the purification of chemicals via chromatography and distillation.Maintaining a well-organized and detailed lab notebook with accurate descriptions of the chemistry and observations to enable the preparation of technical packages/technical transfers and accurate replication in receiving labs.Participate in training, mentoring, and supporting chemists in safe and practical process chemistry techniques during demonstrations and material preparations.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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