**For Current Gilead Employees and Contractors:** Please log onto your Internal Career Site (https://www.myworkday.com/gilead/d/inst/13102!CK5mGhIKBggDEMenAhIICgYI1A0QtgI~/cacheable-task/2997$2151.htmld#backheader=true) to apply for this job. At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. **Job Description** The primary responsibility of this position is to design and conduct or monitor experiments to understand the metabolism and drug-drug interaction (DDI) properties of drug candidates, particularly the quantitative roles of enzymes in the disposition of those drug candidates (metabolic phenotyping). More broadly, the scientist is expected to integrate this information with absorption, distribution and excretion data for these compounds for a full understanding of their drug metabolism and pharmacokinetic (PK) behavior. This will include representation of the department on multidisciplinary project teams. Supervision and mentoring of other scientists and/or laboratory staff will be required. This role will be based in our headquarters in Foster City, CA. **Essential Duties and Job Responsibilities:** + Through guidance of other staff and external resources, and through direct laboratory work conduct studies to determine the kinetics of metabolism of drug candidates and to determine the roles of various enzymes in the metabolic profiles of those compounds. + Serve as a drug metabolism and enzyme kinetics subject matter expert for multiple dynamic cross-functional teams, to define strategies to achieve target product profiles, integrate in vitro and in vivo drug disposition data, interpretation, and give presentations to teams. + Work closely with internal and external resources to assure timely delivery of high-quality data. + Provide clear verbal communication of results and strategies at group, department, project team and management level. Write research reports and regulatory documents. + Contribute to science through conference presentations and publication of new findings. **Basic Qualifications:** Bachelor's Degree and Twelve Years’ Experience OR Masters' Degree and Ten Years’ Experience OR PhD and Eight Years’ Experience **Preferred Qualifications:** + A highly motivated individual with PhD degree in life sciences with 8 - 10 years of post-doctoral and/or industry experience directly related to the Specific Responsibilities listed above (hands-on experience and deep knowledge of enzymology and enzyme kinetics). + A significant advantage would be hands-on experience in application of the enzymology data in physiologically-based PK (PBPK) modeling (using e.g. Simcyp, GastroPlus or custom models) + Demonstrates excellent scientific verbal and technical communication, and interpersonal skills. Must be organized, pay attention to details and have strong organizational and planning skills. + Expertise and experience in one or more of the following areas: + Experience in drug development, authoring documents for regulatory authorities + Deep understanding of the principles, theories and approaches of PK, drug disposition and drug interactions. Proven application of modeling methods for quantitative translation using Simcyp, GastroPlus and/or general kinetic modeling programs. + State of the art bioanalysis by LC/MS and related techniques **People Leader Accountabilities** + Create Inclusion - knowing the business value of diverse teams, modeling inclusion, and embedding the value of diversity in the way they manage their teams. + Develop Talent - understand the skills, experience, aspirations, and potential of their employees and coach them on current performance and future potential. They ensure employees are receiving the feedback and insight needed to grow, develop, and realize their purpose. + Empower Teams - connect the team to the organization by aligning goals, purpose, and organizational objectives and holding them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem. The salary range for this position is: $226,185.00 - $292,710.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. **For jobs in the United States:** As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' (https://www.eeoc.gov/employers/eeo-law-poster) poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT (http://www.dol.gov/whd/regs/compliance/posters/eppac.pdf) YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp\_%20English\_formattedESQA508c.pdf) Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. **For Current Gilead Employees and Contractors:** Please log onto your Internal Career Site (https://www.myworkday.com/gilead/d/inst/13102!CK5mGhIKBggDEMenAhIICgYI1A0QtgI~/cacheable-task/2997$2151.htmld#backheader=true) to apply for this job. Gilead Sciences, Inc. is a biopharmaceutical company that has pursued and achieved breakthroughs in medicine for more than three decades, with the goal of creating a healthier world for all people. The company is committed to advancing innovative medicines to prevent and treat life-threatening diseases, including HIV, viral hepatitis and cancer. Gilead operates in more than 35 countries worldwide, with headquarters in Foster City, California.