Job Description

A. Position Objective

We are looking for a highly motivated individual with expertise in drug design, synthesis, as well as small molecule drug development and evaluation. The overall role is to work on small molecule drug evaluation and validation, and work closely with biologists in the team for assay development and experimental design.

B. Duties and ResponsibilitiesUtilize expertise in drug synthesis and small molecule drug development to lead the initial assessment and screening of small molecule projects, identifying those with the potential for further evaluation and development.Conduct in-depth analysis of molecule structures, synthetic routes, and compound properties, integrating molecular and functional group assessments to ensure comprehensive and reliable drug evaluation, and monitor project progress for developmental efficiency.Provide critical insights to guide decision-making on potential collaborations, leveraging expertise in small molecule projects.Drive and oversee the execution of small molecule project milestones, ensuring coordinated data verification, quality control, and strategic guidance to support innovative collaborations with partners and advance project goals.Offer strategic recommendations for optimizing small molecule compound structures, physicochemical properties, and synthesis routes, contributing to the enhancement of project efficiency and success.Collaborate closely with the biology team to develop assays and experimental designs, facilitating an integrated approach to small molecule drug evaluation.Develop and expand capabilities in the evaluation and collaboration of RNA and peptide-based drug projects, contributing to the exploration of innovative and potential high-impact projects.

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully 
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.  No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. 

Employee Status:

Regular

Relocation:

No relocation

VISA Sponsorship:

No

Travel Requirements:

No Travel Required

Flexible Work Arrangements:

Not Applicable

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

no

Job Posting End Date:

08/31/2025

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R343466