The Leclerc Laboratory at the University of Virginia, Department of Anesthesiology, seeks applications for a Lab and Research Technician 1 or 2, Applicants will be considered for a Lab and Research Technician position 1 or 2 based on the degree of their prior education and laboratory experience.
Department of Anesthesiology provides an environment where expertise and passions thrive, utilizing our extraordinary team of anesthesia physicians, trainees, nurses and staff to advance patient care within UVA Health. With excellence in physician leadership, research, education and innovations, we strive to improve perioperative outcomes, establish unparalleled practices in patient care, and advance the field of anesthesiology globally. Clinical and Basic Science Research are an essential part of the mission in the UVA Department of Anesthesiology.
The Leclerc Lab focuses on elucidating the mechanisms for the clearance of neurotoxic metabolites from the brain following hemorrhagic stroke. Normally, blood is not present within the brain aside from that which is contained within the vasculature. When bleeding occurs, extravascular red blood cells become unstable and release a myriad of neurotoxic molecules. The glymphatic pathway is a special clearance pathway within the brain that facilitates bulk flow washout of molecules to the periphery. This research focuses on how various anesthetic paradigms modulate the glymphatic pathway to augment the clearance of neurotoxic metabolites after hemorrhagic stroke.
The experiments proposed utilize cutting-edge in vivo and in vitro techniques and represent a unique research niche that bridges the fields of Anesthesiology and Neuroscience. This position will require the ability to perform both routine lab functions as well as more advanced neuroscience procedures and protocols. Routine lab functions may include managing the mouse colony, genotyping, making solutions, ordering lab supplies, maintaining inventories, and organizing and maintaining records and lab SOPs. Advanced neuroscience procedures may include performing stereotaxic and other survival surgeries on mice, two photon microscopy, complex brain magnetic resonance imaging (MRI) protocols, administering pharmaceutical agents to mice, neurobehavioral monitoring of mice, and performing sectioning, histology, western blotting, and other forms of microscopy. In addition to the above job responsibilities, other duties may be assigned.
This position will report to the Principal Investigator (PI). All team members meet individually with the PI at least weekly to summarize their progress and troubleshoot their projects. They will also work closely with other lab members and team members within the Departments of Neuroscience and Anesthesiology.
For additional information about the position, please contact Jenna Leclerc, MD, PhD at cxx3cm@virginia.edu
Minimum Qualifications:
-Lab and Research Technician 1
Education: High school diploma or equivalent
Experience: At least 1 year of lab experience, which may include student experience. Bachelor's degree will be considered in lieu of experience.
-Lab and Research Technician 2
Education: Associate's degree
Experience: At least 2 years of lab experience which may include student experience. Bachelor's degree in related science will be considered in lieu of experience.
Preferred Qualifications:
Bachelor’s or higher degree in field of neuroscience and/or pharmacology or related field of study
Over 3 years of laboratory experience working with rodents
Prior experience with survival surgeries, in particular with stereotactic surgical procedures
Interest in basic neuroscience, stroke, and/or anesthesiology research
Experience with neurobehavioral monitoring in mice
Experience with sectioning and histology
Experience with in vivo imaging of rodents (e.g. two-photon microscopy and MRI)
Proficient in Microsoft Office Suite (Word, Excel, PowerPoint).
Strong data analysis and problem-solving skills.
Excellent organizational and time management abilities.
Ability to work effectively both independently and as part of a team.
Comfortable handling rodents.
This position is a restricted position and is dependent upon project need, availability of funding and performance. This is a Non-Exempt level, benefited position. For more information on the benefits at UVA, visit hr.virginia.edu/benefits.
This position will remain open until filled. The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.
References will be completed via UVA’s standardized process Skill Survey. A total of five references will be requested via SkillSurvey during the final phase of the interview process.
Physical Demands:
This position is located in Charlottesville, VA This position can spend extensive periods of time standing and squatting while conducting experiments or caring for animals. Also requires keyboarding and other bench work and animal procedures requiring finer finger manipulation.
Anticipated Hiring Range:
$37,000 - $47,000, based on education and experience.
To Apply:
Please apply through Careers at UVA , and search for R0067204
Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs.'
Complete an application online with the following documents:
CV
Cover letter
Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all required documents will not receive full consideration.
For questions about the application process, please contact Yelena Markazyan, Academic Recruiter at ym3mm@virginia.edu
For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/
The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex, pregnancy, sexual orientation, veteran or military status, and family medical or genetic information.