**Job purpose** + Lead and develop product medical strategy and plan based on product strategy. + Key member in the brand team to develop product strategy with and local commercial team. + Provide Japan position on global/region disease and product related programs. + Provide medical affair consideration on portfolio evaluation and discussion. + Lead the planning and execution of evidence generations, publications and medical events. **Key responsibility** + Partners with the brand team in the development and execution of the Local product(s) lifecycle management plan + Leading and developing the Local Medical strategy and Medical activities for the product(s) in accordance to internal and external regulations + TA and/or product specific Medical training + Ensuring consistency of Medical content and scientific messages across various tools and materials + Visits selected KOL’s and study groups for strategic discussions and protocol development + Develops study protocols for Local Amgen sponsored studies (AST); supports and executes Local study protocol preparation, filing, review and approval in line with + Amgen processes and policies + Works with Global Study Operations (GSO) to ensure preparation, implementation and completion of ASTs + Supports GSO in participation and completion of global/region studies in the country, including provision of input into site selection + Reviews Local ISS proposals prior to approval and ensures appropriate + Local/region/global committee review, if applicable + Oversees in-sourced/out-sourced medical programs and logistics + Participates in/conducts Local Advisory Board Meetings, Investigator Meetings and/or Expert Panels + Provides Medical expertise for pipeline products + Provides Medical expertise for Health Economy and reimbursement requests **Basic Qualifications** + Master’s degree in life-science or relevant area, equivalent education history + Experience and knowledge in relevant therapeutic area (Cardiovascular) + Minimum of 2 years in pharmaceutical industry, or proven industry collaboration in academia + Experience in Medical Department or Clinical Development + Experience with clinical study management and conduct + Knowledge of commercialization and business practices + Fluent in Japanese and English **Preferred Qualifications Preferred Requirements** + MD, PharmD or PhD is strongly preferred + Knowledge of pharmaceutical product development, product lifecycle and commercialization process with advanced understanding of other functions; including, but not limited to, Clinical Operations, Commercial, Regulatory, and Medical Affairs + Therapeutic area knowledge and experience is preferable + Network of customer contacts in therapeutic area + Finance and budgeting experience + Capability of office works and project managements **Competencies** + Medical/scientific expertise, and business acumen + Fluency in English, both oral and written communications + Strong communication and presentation skills + Continuously expanding medical and scientific knowledge as well as + market knowledge + Strong clinical research knowledge (study design, study evaluation, medical writing skills, expert panel conduct, symposium and workshop management, KOL management) + Strong customer orientation; science-based + Ability to work in a cross-functional team (e.g., Commercial, Clin Development, EU teams, HE, Regulatory, Safety, etc.) + Role model for others in line with Amgen Values + Demonstrates leadership skills