Defined by golden standards of long-term self-renewal and multi-lineage differentiation, stem cells (SCs) come in different flavors. In mammals, adult SCs are essential units to orchestrate postnatal remodeling and repair damage. In contrast to steady state, SCs in coping with stress often expand their fates and embark on behaviors distinct from their homeostatic patterns, known as plasticity. While plasticity is essential for organismal survival, its derailed regulation poses disease vulnerability to individuals, especially those undergoing prolonged stress. Under these scenarios, SCs are subjected to functional exhaustion frequently observed in aging, or malignant transformation that occurs in cancer. Research in the Ge lab applies principle of developmental biology in order to understand molecular mechanisms underlying SC plasticity, and how its deregulation leads to human diseases. Incoming postdoc fellow will lead Ge lab's research direction investigating SC plasticity in skin cancer. **LEARNING OBJECTIVES** Carry out mouse genetics experiments and mechanistic studies, perform bioinformatic analysis, document findings, write manuscript and fellowship applications, for future independent academic research positions. **ELIGIBILITY REQUIREMENTS** PhD (within three years) in biomedical sciences. **POSITION INFORMATION** MD Anderson offers full-time postdoc positions with a salary ranging from $64,000 to $76,000 (https://trainees.mdanderson.org/apply/mdaPostdoctoralFellowStipendFY24.pdf) . depending on the number of years of postgraduate experience. The University of Texas MD Anderson Cancer Center offers excellent benefits (https://www.utsystem.edu/offices/employee-benefits/insurance-0/eligibility) , including medical, dental, paid time off (https://www.mdanderson.org/about-md-anderson/employee-resources/leave.html) , retirement (https://www.utsystem.edu/offices/employee-benefits/ut-retirement-program/voluntary-retirement-programs) , tuition benefits, educational opportunities, and individual and team recognition12/01/2025