USA
9 days ago
Postdoctoral Research Associate
Job Title Postdoctoral Research Associate Agency Texas A&M Agrilife Research Department Biochemistry & Biophysics Proposed Minimum Salary Commensurate Job Location College Station, Texas Job Type Staff Job Description Genetic Analysis of Lipid Asymmetry and Membrane Dynamics The laboratory of Dr. Ann Wehman in the Department of Biochemistry and Biophysics at Texas A&M University in College Station, Texas, USA is recruiting a postdoctoral fellow to help create the first phosphatidylethanolamine (PE) sensor. We predict this will be a transformative innovation that will contribute to many scientific fields. The Wehman lab uses genetic and imaging approaches to determine the molecular mechanisms of extracellular vesicle budding. We discovered that regulators of lipid asymmetry also regulate outward budding of the plasma membrane to form extracellular vesicles (EV), specifically regulators of phosphatidylethanolamine (PE) asymmetry (see Wehman et al., Curr Biol 2011, Beer et al., PNAS 2018). PEs are poorly understood lipids with provocative roles during the final step of cell division in addition to EV budding, but there are no genetically encodable probes for PE species to enable the study of their dynamics in animals. https://bcbp.tamu.edu/people/wehman-ann/ The position is initially funded by a collaborative grant from the Allen Frontiers group. https://alleninstitute.org/division/frontiers-group/distinguished-investigators/extracellular-vesicles-in-maintenance-of-neuronal-circuitry/ Highly motivated candidates with a Ph.D. in biological, chemical, or physical sciences and an interest in cell biology are encouraged to apply. Interested candidates should apply in Workday including a cover letter detailing their interests and expertise, their CV including a publication list, and the contact information for at least two references. Qualifications Required Education: -Ph.D. in biological, chemical, or physical sciences Preferred Experience: -Experience in a molecular biology, biochemistry, or structural biology lab Required Special Knowledge, Skills, and Abilities: -Excellent communication skills (both written and spoken). -Ability to work both independently and as part of an international team. -Ability to multi-task and work cooperatively with others. -Ability to utilize a computer and applicable software to create databases, perform statistical analyses, present data and perform other computer related tasks, such as Microsoft Office, Preferred Special Knowledge, Skills and Abilities: -ImageJ and Matlab. -Expertise in biosensors or protein design -Familiarity with genetic model organisms, microscopy, and other appropriate laboratory and/or technical equipment **Position is contingent on grant funding** Job Responsibilities 50%: Lab research - Design, plan, conduct and coordinate experiments in a wet lab as well as using computers. 20%: Communication - Keep detailed records of data and share regular updates with PI. - Summarize results for inclusion in scientific and grant-oriented publications and presentations. - Present results at local, regional, national, and international conferences. 20%: Mentoring - Supervise undergraduate and graduate students and other laboratory or technical staff involved in research. 10%: Other Duties - Perform other duties as assigned. All positions are security-sensitive. Applicants are subject to a criminal history investigation, and employment is contingent upon the institution’s verification of credentials and/or other information required by the institution’s procedures, including the completion of the criminal history check. Equal Opportunity/Affirmative Action/Veterans/Disability Employer.
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