The Dana-Farber Cancer Institute seeks a Research Fellow to focus on next-generation, translational pathology studies who will work within the Wolpin-Nowak laboratory as part of the Hale Family Center for Pancreatic Cancer Research (http://halecenter.dfci.harvard.edu) and the Lustgarten Foundation Pancreatic Cancer Research Laboratory at the Dana-Farber Cancer institute (https://www.lustgarten.org/research/our-lab/). The Wolpin-Nowak laboratory studies the epidemiology and biology of pancreatic ductal adenocarcinoma (PDAC). The pathology portion of the laboratory is focused on multimodal characterization of human PDAC specimens from large landscape cohorts as well as specimens collected for clinical trial correlative studies. We employ and develop genomic, transcriptomic, and protein-based techniques to study PDAC and its microenvironment with a focus on digital imaging, spatial technologies, and automated analysis pipelines driven by machine learning. Members of our lab collaborate extensively with other laboratories in the Hale Center, including those focused on mouse and experimental model systems, immunology, and mathematics/bioinformatics, in order to maximize the information we can generate from human tumor specimens.
*This role is heavily pathology focused and requires Multiplex Immunofluorescence (mIF) experience.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities Design and conduct studies using multiplex immunofluorescence, spatial transcriptional profiling, and other high-dimension tissue analysis approaches to evaluate pancreatic cancer pathology using human tissue specimensAssemble analysis pipelines using machine learning to process tissue data reproducibly and at scaleConduct analyses using programming languages such as R and PythonCollaborate with other laboratory members with expertise in epidemiology, bioinformatics, pathology, molecular biology, and functional genomicsParticipate in group meetings and work collaboratively on larger projects with other group membersLead projects that result in first author manuscriptsWrite grants and progress reports related to research funding
KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:
Strong background in human pathologyExperience with traditional pathology laboratory techniques, including slide sectioning, H&E staining, immunohistochemistry and special stains a plusExperience with translational pathology technique, including multiplexed immunofluorescence, spatial transcriptomics, and RNA in situ hybridization a plusExperience with digital image analysis platforms (Halo, VisioPharm, QuPath, InForm, etc.) a plusExperience with R, Python, and commonly used libraries/packages a plusEnthusiasm for novel assay and technology developmentAbility to independently analyze information and troubleshoot when requiredExcellent written and verbal communication skillsAttention to detail and thoroughness in completing work tasksAbility to work within a team environmentAdaptability to a fast-paced, dynamic environment Qualifications Candidates should hold a doctoral degree in genetics/genomics, cancer biology, pathology or related fields. Multidisciplinary training and experience in multiple of these fields is desirable. MD or MD-equivalent and PhD-holding candidates will both be considered; MD/PhD-holding candidates with pathology training are highly encouraged to apply.Prior miF Experience requiredAt Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEOC Poster
Options Apply for this job onlineApplyShareEmail this job to a friendRefer Sorry the Share function is not working properly at this moment. Please refresh the page and try again later. Share on your newsfeedSoftware Powered by iCIMS
www.icims.com