A post-doctoral position is available in the laboratory of Dr. Ranmal Samarasinghe in the Department of Neurology at the University of California, Los Angeles (UCLA). The Samarasinghe laboratory utilizes human stem cell derived brain organoid models to study the fundamental mechanisms underlying neural circuit development, and the impact of neurological disorders including (but not limited to) epilepsy, autism, and Alzheimer’s Disease on circuit formation and function. Our laboratory is at the forefront of utilizing advanced approaches for developing electrophysiologically competent human brain organoids that can generate complex network electrodynamics. We apply several techniques including cutting edge electrophysiological recording approaches, computational modeling, next-gen omics, and advanced imaging to interrogate developmental pathways and circuit function in our organoid models. We are particularly interested in how human pathogenic single gene variants impact circuit development and function and have a developed a pipeline for using human IPSCs from patients with these disorders to generate our organoid models. To achieve our goals, we have long-standing collaborations with leading research laboratories at UCLA and elsewhere, and trainees in our laboratory will have ample opportunities to receive mentorship and expert training from collaborators, in addition to the training within own group. The laboratory environment is highly collegial and interactive. Please visit our lab website for further details https://samarasinghelab.com/.
Salary Rand is $66737-$80034.
UCLA has been ranked the No.1 public school in the US by U.S.News in 2024. The rich scientific environment provides unparalleled research training opportunities, including research seminars given by scientific leaders around the world, exposure to diverse research programs, cross-disciplinary collaborations, and many highly sophisticated core facilities.
Successful candidates for post-doctoral positions are expected to have a PhD degree with a strong record of publication and should be highly motivated, collaborative, and able to conduct independent research. Candidates with a strong background in stem cell biology, genetics, developmental biology, electrophysiology, or neuroscience are particularly encouraged to apply. The candidate will perform independent research based around the theme of neural circuit development and function under the direction and Dr. Samarasinghe and will be expected to write manuscripts, apply for grants, and will have the opportunity to present their work at international conferences once the work is adequately developed. These are fully funded multi-year positions.
A highly competitive salary commensurate with experience will be provided. Applications should be sent to Dr. Ranmal Samarasinghe (rsamarasinghe@mednet.ucla.edu). Please include your detailed curriculum vitae, a statement of research interests describing your background and research interest, and the contact information of three references.

Application procedure: Apply by submitting your application to our online RECRUIT system
at https:/ / recruit.apo.ucla.edu/ JPF09844 along with CV, statement of research, and 3 references (optional). Screening of applicants will begin immediately and will continue until the position is filled.
Please be advised that the final candidate recommended for hire into a critical (or otherwise designated) position will be required to successfully complete a background investigation. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
The offer of this position is contingent on the successful completion of a background check prior to your first day of employment and evidence of authorization to work in the United States. Also by accepting this offer you are acknowledging compliance with UCLA Health policy by receiving your influenza vaccination prior to your start date. If you are in agreement with the terms and conditions of this offer, please sign and return the enclosed copy of this letter. Feel free to contact Jacqueline Linares at 310-206-6567 to discuss any questions you may have regarding employment.
The University of California is an Equal Opportunity/ Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy. UC Nondiscrimination & Affirmative Action Policy.
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