The Hill Laboratory seeks an intellectually curious, team-oriented, and motivated postdoctoral scholar to investigate questions related to molecular and cellular mechanisms of interoception and kidney physiology in mice. We seek to understand how sensory nerves regulate the function of internal organs under healthy and diseased states. The kidneys are essential regulators of homeostasis within the body, and, as such, we are studying renal interoception with the goal of unraveling the molecular and cellular mechanisms by which sensory nerves influence key physiological processes in vivo. In the past, we found that sensory nerves innervate key functional structures within the kidney. Recently, we are interested in testing the function of these nerves in health and disease using modern neuroscience approaches in mice, including but not limited to: in vivo calcium imaging of sensory neuron activity, optogenetic manipulation of sensory nerve activity with monitoring of kidney function, electrophysiology, perturbation of renal sensory nerve function in animal models of kidney disease and inflammation, single cell RNA-seq, and histological, anatomical, and/or functional characterization of renal sensory nerves and circuits. This is a wide-open and burgeoning field of neuroscience that the successful applicant will explore under the guidance and mentorship of Dr. Hill.
Interested applicants should send a cover letter describing research experience, future interests pertaining to the Hill Lab, career aspirations, and a CV.
Function/Duties of PositionThe scholar will receive training in areas related to their specific project and will also be encouraged to seek out relevant collaborators within and outside the institution with the help of Dr. Hill. The successful applicant will work on at least one project and will have expertise and demonstrated interest in neuroscience, kidney biology, cardiovascular function, and/or physiology. Dr. Hill aims to provide rigorous hands-on training in project design, securing independent funding through grant and fellowship applications, delivering effective research presentations, forging collaborations, writing and publishing manuscripts, and other skills necessary for the applicant to one day run their own independent research group.
In addition to duties related to their independent research, the successful applicant will be expected to apply for independent funding to support their research, to assist Dr. Hill in applying for independent funding related to the project, and to regularly present and communicate their results to Dr. Hill and the laboratory. Additionally, the candidate will receive regular career mentoring and guidance from Dr. Hill, and it will be expected that the independent research of the candidate be prepared for publication in one or more peer-reviewed scientific articles in collaboration with Dr. Hill. Most projects in the lab involve significant mouse work. Preference will be given to candidates with a strong background in rodent behavior, optogenetics, single cell transcriptomics, rodent survival surgeries, AAV work, neuroscience techniques, and/or in vivo imaging.
Required Qualifications PhD in related field.Research experience in neuroscience, physiology, kidney biology, cardiovascular biology, and/or cell biology.Ability to communicate effectively, in both written and oral formats.
Demonstrated independence in preparing and delivering quality oral presentations and manuscripts.
High level of self-motivation and integrity.
Demonstrated track record of completing independent research in one or more of the required Experience areas.
Preferred Qualifications One or more of the following areas of expertise: rodent behavior, optogenetics, single cell transcriptomics, rodent survival surgeries, AAV work, neuroscience techniques, and/or in vivo imaging.Demonstrated independence in securing fellowships and funding. All are welcome Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.