Welcome page Returning Candidate? Log back in! Postdoctoral Scholar Job Locations US-OR-Portland Requisition ID 2023-24339 Position Category Postdoctoral Position Type Regular Full-Time Job Type Postdoctoral Department CEDAR - Knight Cancer Institute Salary Range DOE FTE 1.00 Schedule Monday through Friday Hours 8:30am to 5:00pm plus occasional nights and weekends HR Mission School of Medicine Drug Testable No Department Overview

Overview: The Cancer Early Detection Advanced Research (CEDAR) center is a collaborative institution within the OHSU Knight Cancer Institute. The Knight Cancer Institute, known as one of the pioneers in personalized cancer medicine, is an international leader in research and cancer treatment. At CEDAR our mission is to detect and stop lethal cancers at the earliest stage because early detection saves lives. This is an ambitious goal, one that requires novelty, creativity, and innovation. We are comprised of biologists, chemists, biomedical engineers, computationalists, and clinicians conducting groundbreaking translational cancer research to help people maintain a high quality of life and reduce cancer mortality, to create a global early detection community, and to have a positive impact on the Oregon economy.

 

Our Commitment to Diversity: CEDAR is committed to increasing the diversity of the campus community. We are dedicated to promoting inclusion and multiculturalism by having outstanding researchers of diverse backgrounds work together on multiple projects. We encourage high-risk, high-reward research projects because defeating cancer requires out-of-the-box thinking and new perspectives. Our research is milestone driven to ensure that each project is fulfilling its stated goals.

 

Every Knight Cancer employee is expected to embody our guiding principles:

We act BOLDLY—Breakthroughs require pushing the boundaries of science, exploring new frontiers, and thinking differentlyWe SUPPORT each other—Respect leads to trust, which leads to excellenceWe work as a CONNECTED team—We must leverage our collective brain power to conquer cancer because no one individual can do it alone Function/Duties of Position

A successful candidate will have the opportunity to work under the mentorship of Dr. Joshua Saldivar to investigate key questions on nuclear dynamics that maintain the stability of genetic and epigenetic information. We are currently seeking a highly motivated fellow with expertise in molecular biology, cell biology, and/or epigenomics to work in the following NIH-funded areas:

Coordination of DNA replication and transcription – uncover mechanisms that spatially-separate replication and transcription zones, study S phase-specific transcription regulatory mechanisms that prevent transcription-replication conflicts, investigate dynamics of phase-separated transcription condensates across S phase.DNA replication stress – induced epigenetic instability – determine the impact of replication stress on propagation of epigenetic information, uncover mechanisms that couple DNA replication to epigenetic stability, explore the role of balanced histone synthesis on maintenance of epigenetic information. Novel ATR-CHK1 signal transduction pathways – investigate ATR-CHK1 regulation of transcription-related cyclin-dependent kinases, including CDK12, CDK13, CDK8, and CDK19; signaling and regulation of histone locus body processes; and phase-separation of mediator complex. Required Qualifications M.D., M.D./Ph.D., or Ph.D.Minimum of 3 years as a graduate studentSpecialty: Molecular Biology, cell biology, genome sciences, epigenomics, or related field Excellent communication, analytical and organizational skillsAbility to work independently and as part of a team while being collaborative in resolving problemsPassion for science and inquiryAbility to synthesize one’s own results and others to formulate hypothesesAbility to prioritize multiple tasks at one timeMust possess energy and drive to coordinate multiple projects simultaneouslyAbility to use tact and diplomacy to maintain effective working relationships Preferred Qualifications Ability to synthesize scientific projects and communicate science to diverse audiencesExperience with cell cultureExperience with microscopyExperience with NGSExperience with data analysis Additional Details

Apply online. Please be sure to upload a Cover Letter and Resume/CV.

 

We offer a variety of benefits on top of joining a thriving organization:

Medical, dental and vision coverage at no or low cost to employeesCovered 100% for full-time employees and 88% for dependentsSeveral retirement plans to choose from with contributions from OHSU80 hours per year of vacation time96 hours of sick leave a year (prorated for part-time employees)Commuter subsidiesTuition reimbursementAccess to group life insurance, disability insurance and other supplemental benefitsAnnual RaisesGrowth/Development OpportunitiesEmployee discounts to local and major businesses

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All are welcome Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.