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Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

Position Summary:

This Postdoctoral Scientist position offers the opportunity to be part of Lilly Oncology’s Advanced Molecular Design team focused on building deep insights into structure-function relationships in medicinal chemistry. The scientist will work in a multidisciplinary team environment designing and synthesizing medicinal chemistry targets and developing experimental methods which can rapidly advance discovery efforts.

Responsibilities:

Working within a scientific team, conceptualize and execute new methodologies to rapidly screen relevant reactions.

Design new medicinal chemistry targets that optimize for potency, ADME, and physiochemical properties.

Synthesize new medicinal chemistry targets that optimize for potency, ADME, and physiochemical properties.

Purify starting materials, intermediates, and final compounds

Characterize reaction components including starting materials and products by modern analytical techniques including LCMS, NMR, etc.

Review assay data, communicate results, and discuss project impact of new data

Uphold laboratory safety standards and safe chemical handling practices

Generate accurate and descriptive lab records in a timely manner

Present their work and participate in team meetings

Work collaboratively in a laboratory environment including maintaining and troubleshooting laboratory instrumentation and equipment

Basic Requirements:

PhD in organic chemistry, chemistry, biochemistry, or related field

Additional Preferences:

Self-motivation and continual learner mindset

Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, and staff at all levels.

Experience or familiarity with parallel reaction design, design of experiments, or high-throughput synthesis

Experience or familiarity with biocatalysis, directed evolution, site-directed mutagenesis, and protein purification and characterization.

Experience or familiarity in data science

Experience or familiarity with Python, R, or other coding languages

Experience or familiarity with the use of molecular modeling software packages including molecular dynamics, classical mechanics, and quantum mechanics methods.

Strong interest in creating and advancing new technologies in predictive data chemistry

Excellent organizational, analytical, documentation and multi-tasking skills

Demonstrated track record of creative problem solving

Additional Information:

Physical Demands:

The physical demands of this job are consistent with a lab environment.  

 The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment:

This position’s work environment is in a Laboratory.  

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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