**HOW MIGHT YOU DEFY IMAGINATION?** If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Precision Medicine Therapeutic Area Lead **Live** **What you will do** Let’s do this. Let’s change the world. In this vital role you will act in conjunction with the Obesity Therapeutic Area head to advance the development and execution of Precision Medicine objectives. Lead a cross-functional team to develop and execute translational and precision medicine strategies to support asset (and above-asset, as needed) development across the product lifecycle. Additionally, partner with cross functional Therapeutic Area leads across Research & Development to guide the development of translational, reverse translational, and precision medicine strategies. + Serve as the strategic integrator of various stakeholder inputs and multiple lines of evidence for the development of translational medicine and precision medicine strategies at asset and/or indication level. + Set strategic vision to enhance the value of the asset across the product lifecycle through clinical biomarker target identification, indication selection, early indication of biological activity and patient stratification/selection including reverse translation strategies. + Course correct as needed by incorporating deep mechanistic insights and –omics signatures into actionable precision medicine strategies. + Lead cross-functional teams in the development and execution of phase appropriate, integrated, biomarker and human data plans, to support translational pharmacology and inform patient selection strategies. + Serve as the key liaison between research and development by providing clinical translational considerations (proof of target engagement, dose selection, patient selection) to inform discovery asset development as well as enabling reverse translational strategies (to gain mechanistic insights related to patient stratification, response/resistance) for assets in clinical phase. + Provide precision medicine considerations to shape disease area strategies (disease endotypes, indications, and combinatorial approaches). Provide subject matter expertise to inform registrational and access and use evidence generation plans. + Work cross-functionally to evaluate appropriate data sources and strategies for translational/precision medicine execution and propose funding/collaboration needs to appropriate Commercialization Governance Forums. **Win** **What we expect of you** We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications. **Basic Qualifications:** Doctorate degree and 4 years of relevant experience OR Master’s degree and 7 years of relevant experience OR Bachelor’s degree and 9 years of relevant experience **Preferred Qualifications:** + MD & PhD with 6+ years industry & academic experience + Deep scientific and analytical expertise in integrating multiple data sources e.g. –omic, clinical, Real world evidence (RWE) to inform precision medicine approaches + Strong professional network with external Key Opinion Leaders, academic institutions, and industry partners + Experience in translational research and/or advancing clinical candidates + Knowledge of Good Clinical Practices (GCP) and applicable regulatory requirements for biomarker and diagnostic development + Proven ability to lead, manage, and motivate others in a complex, multi-functional matrix environment + Exceptional leadership and team management skills **Thrive** **What you can expect of us** As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: + Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. + A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan + Stock-based long-term incentives + Award-winning time-off plans and bi-annual company-wide shutdowns + Flexible work models, including remote work arrangements, where possible **Apply now** **for a career that defies imagination** Objects in your future are closer than they appear. Join us. **careers.amgen.com** **Application deadline** **Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.** Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation \#obesity