**Working with Us** Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . **Bristol Myers Squibb Ireland** Bristol Myers Squibb has been in operation in Ireland since 1964, employing over 650 people across a range of activities and business units. Ireland is home to External manufacturing's global headquarters, the business unit responsible for the management of manufacturing contract operations (CMO's) and ensuring reliable supply of product to patients across the Bristol Myers Squibb global network. This includes management of, and working in conjunction with, third party contract manufacturers and internal manufacturing sites. In Ireland, External Manufacturing has two sites; Global Headquarters based in Dublin 15 and a distribution centre in Shannon, Co Clare. For more information about Bristol Myers Squibb, visit us at BMS.com/ie **The Role** BMS External Manufacturing is looking to recruit on a permanent Contract Principal Scientist, Pharma Manufacturing Science and Technology (MS&T), reporting to Director, MS&T Pharma DP Commerical. The Pharma Manufacturing Science and Technology (MS&T) Senior Manager / Principal Scientist provides technical support to the External Manufacturing Organization and (ExM) Contract Manufacturing Organizations (CMOs). **Key Duties and Responsibilities:** + Support CMO/vendor selection process - preparation of technical information packages, participation in due diligence and site assessments, technical evaluation of Requests for Information (RFIs) and Request for Proposal (RFPs). + Accountable for technology transfer to contract manufacturing organisations. + Support regulatory activities associated with changes to assigned products . + Support operational management of CMO as per Virtual Plant Team (VPT) governance structure + Provide ongoing technical support to ExM / CMO to ensure compliance and security of supply - metrics review, investigation close-out, change control review, Annual Product Quality Review (APQR) review, process improvement. Implement / OPEX initiatives as necessary. + Represent MS&T on VPT and project teams. Works closely with Supply Relationship Manager and project team members in developing strategies and problem-solving efforts. + Where appropriate, engage with brand teams and ExM business units to raise awareness and manage/mitigate risks to product supply, supporting the identification of continuous improvement and business continuity projects. + Product robustness - + Technical lead/ product owner for creation of robustness monitoring plan, control strategy + provides technical oversight to ensure continuous process monitoring for all products within scope. + Communicating output of product performance reviews with VPT and others groups as required + Identifying and executing robustness improvement projects, where required **Qualifications, Knowledge and Skills Required:** + Must have in-depth knowledge of bulk drug product - recognized as a technical leader and subject matter expert Oral Solid Dosage (OSD), Semi-solids, Liquids, Sterile/Aseptic products manufacturing. + Experienced with use of statistical software to analyze process related data to determine process capability or for troubleshooting purposes. + Proficient in the technical transfer of products to CMOs within budget and according to project timeline. Demonstrated ability to project manage one or more tech transfer projects with minimal supervision. + Substantial experience of manufacturing support activities (change control, investigations, process optimisation) + Excellent verbal, written communications and presentations skills, including excellence at writing complex study plans and scientific reports; informed line management about the critical issues related to product manufacturing and process / package validation where appropriate. + In depth understanding of regulations concerning cGMP, manufacturing/packaging/artwork, validation, quality systems, equipment innovations, upgrades, and instrumentation. + Ability to work on own and as part of a team and to drive issues to resolution. + A degree in science or a related field with a minimum of 7 years relevant experience. + Proven record in pharmaceutical technology, technology transfer, process development and manufacturing support/activities. + Experience of statistical software. + Demonstrable experience of analytical method validation. + Ability to interact at all levels of the organisation with proven influencing ability e.g. Regulatory, Supply Chain, CMO, etc. to achieve goals. + Ability to understand business implications of technical decisions. **Why you should apply** + You will help patients in their fight against serious diseases + You will be part of a company that encourages excellence and innovation, respects diversity, develops leaders and values its employees. + You'll get a competitive salary and a great benefits package including, but not only, an annual bonus, pension contribution, family health insurance, 27 days annual leave, access to BMS Cruiserath on-site gym and life assurance. BMSBL **\#LI-Hybrid** If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. **Uniquely Interesting Work, Life-changing Careers** With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. **On-site Protocol** BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. **Company:** Bristol-Myers Squibb **Req Number:** R1586925 **Updated:** 2024-11-13 03:12:21.715 UTC **Location:** Dublin-IE Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.