Armonk, USA
1 day ago
Principal Scientist - Precision Medicine

The individual will work collaboratively with internal and external groups to assure data integrity, best practices for analytics and data visualization, and offering strategic insights to drive Precision Medicine objectives. Successful applicant will join a team of computational scientists from diverse training backgrounds, including but not limited to Statistics, Genetics, Multi-Omics, Proteomics, Chemistry, Engineering, Machine Learning, and Computer Science.

As a Principal Scientist in PMQTS, a typical day may include the following:

Liaise with Precision Medicine Strategy Leads and other key stakeholders to define quantitative strategies for biomarker data types across a range of clinical and CES studies.

Provide statistical expertise on hypothesis testing, data modeling, power analyses, and other applicable quantitative methodologies. 

Provide computational and technical expertise on data cleaning and data visualization. 

Understand technical tools, languages, or custom coding and systems analyses used in the team.

Actively monitor and identify data anomalies and work with data stewards (internal and external) to perform root cause analysis on data quality issues. 

Review integrated complex datasets to ensure the correct application of statistical models on exploratory biomarker data and clinical endpoints. 

Design new computational workflows for novel biomarkers or suggest improvements to existing protocols.

Significantly contribute to the preparation of scientific presentations, manuscripts, and reports, including designing, generating, and final quality checks for publication ready research results.

Effectively communicate analytical plans and timelines for multiple concurrent projects with study team members.

Ability to understand complex biological concepts, applied statistics, and ensure appropriate interpretation of statistical results by the translational team and strategy leads.

Adhere to best coding and data cataloguing practices for business consistency and scientific reproducibility.

This role may be for you if:

You are comfortable working on teams with an open, collaborative culture.

You are self-directed with the ability to work and operate independently within a tight deadline environment.

You are agile and flexible in daily routines and have excellent interpersonal skills, both in person and over the phone. 

You possess a high degree of creativity, latitude, and attention to detail. 

You can multi-task, work on multiple projects, and possess strong organizational skills.

You  have experience with statistical modeling/regression, machine learning, and other relevant data blending abilities (required).

You have experience in at least one of the following scripting languages: R, Python, MATLAB. Other languages such as SQL, Spark, and C++ are a bonus (required).

You have experience working in a Linux and/or cloud, shell scripting, and notebook environment (required). 

You have knowledge of structured data, with the ability to perform data mapping for systems integration, data provisioning, and data consumption (strongly preferred).

You have a working knowledge of clinical trials (strongly preferred).

To be considered for this role, you must have a PhD with 2 years, or Masters with minimum 4 years of relevant work experience in one of the following or otherwise related quantitative fields: Computer Science, Computational Biology, Systems Biology, Quantitative Biology, Bioinformatics, Data Analytics, Statistics, Biostatistics, Applied Mathematics. A working understanding of Clinical trials strongly preferred.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions.  For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process.  Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$126,700.00 - $206,900.00
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