Site Name: Belgium-Rixensart Posted Date: Nov 6 2024 Job Purpose The Principal Scientist is expected to lead, design and execute preclinical scientific studies in support to vaccine project or technological platforms in discovery, development or life cycle management. They may have a team as well to manage. Key Responsibilities Lead the design, planning, organization and analysis of preclinical studies (internal and external), including resources forecasts and activity planification. Direct management or support to N+1 in development and supervision of lab technicians. This implies an adequate presence to the shop floor where the associated activities are performed. May participate to the performance evaluation, development plan of laboratory staff. Share expertise in multiple technical competency domains across the preclinical department BE and possibly across Scientific Areas; Scientific/technology watch in own competency domain within defined mission or project. Lead the development and implementation of new technologies and ensure alignment and state of the art for a given technology across the preclinical department, applying and referring to the GxP/EHS/QA rules in his/her team/lab. Lead the development of new Read Outs/Laboratory Assays (when applicable) Active participation and presentation of lab results in internal meetings, working groups and technical and project team meetings, ensuring quality interpretation and extensive quality check of raw data. Can be the preclinical representative to project teams; when specific expert in one or more techniques, he or she is the principal representative at technical development teams and preferred point of contact for TRD QC, and VCLAP departments with regards to analytical testing or read-outs. Autonomous in decision making within own area of scientific or technical competencies with direct impact on related project strategy Autonomous in writing experimental procedures and scientific reports. Significant contribution (autonomous writing and review by N+1) to and direct interactions with the Regulatory/IP teams for the preparation of the preclinical section of Regulatory/IP documents, in own area of technical expertise Responsible for the immunogenicity testing phase (non-GLP conditions) which is part of GLP Toxicity studies, according to the L-SOP9*5529, when applicable Lead the development / qualification of release/characterization assay and testing of Phase I/II vaccine lots before transfer to ARD, when applicable. May coordinate clinical exploratory testing according to best practices and GSK SOP/Policies, when applicable Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: PhD with 3+ years of post-doc and/or job related experience Area of specialization : Virology (respiratory viruses and/or herpesviruses) and Immunology with a strong expertise in related laboratory assays A good understanding of biopharma/vaccine development process Total education and experience in biopharma - related and in respiratory virus or herpesviruses of at least 8 years Strong expertise in Immunology and Virology mandatory Preferred Qualifications: If you have the following characteristics, it would be a plus: Must have the ability to work with cross-functional teams and communicate effectively Fluent English is a must Sound scientific methodology and thinking Excellent presentation and communication skills Innovative hinking and solution oriented *Li-GSK If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. 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