Position Summary The Klomp laboratories focus on studying kinase and transcription factor-mediated mechanisms of oncogenicity and drug resistance in KRAS mutant cancers. This position includes assisting in coordinating and overseeing laboratory operations such as planning, designing, and conducting experiments, as well as performing data analysis. The MacKeigan laboratory is interested in metabolism and drug discovery in KRAS mutant cancers. This position will include routine animal care and experiments relating to therapeutic tumor models. As part of the MSU community, numerous opportunities will be available for presenting research at meetings and continued education experiences. Responsibilities: + Assist in coordinating research and laboratory operations to meet research goals. + Consult with research supervisor to assist in planning and designing experiments. + Perform experiments and analyze data for research projects. + Operate and maintain laboratory equipment. + Ensure compliance with laboratory safety regulations and procedures. + Help optimize and write protocols for assays used in the laboratory. Communications – Interpersonal relationships: Interacts with: + Graduate and Medical students – assist in scheduling and performing experiments. + Supervisor – meet regularly to receive instructions, exchange information and review data. + Peers/Staff – discuss experimental results, assay optimizations, and division of labor. Present findings at group lab meetings. + Faculty/Researchers – discuss lab analyses and report findings. + Administrators – exchange information necessary for laboratory operations. Minimum Requirements Knowledge equivalent to that which normally would be acquired by completing a four-year college degree program in Cancer Cell Biology or other related science fields; one to three years of related and progressively more responsible or expansive work experience in standard laboratory procedures and safety requirements and performing analytical and research techniques in an area related to research being performed; may require software specific to the area of research; or an equivalent combination of education and experience. Desired Qualifications Experience doing cell and molecular biology (e.g., cell lysate preparation and immunoblots, DNA extraction, PCR, cloning); experience doing mouse in vivo work. Equal Employment Opportunity Statement All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status. Required Application Materials Cover letter, resume/CV, and 3 professional references Work Hours STANDARD 8-5 Description of End Date This is an off-dated position funded for one year from date of hire with possible extension contingent upon funding renewal. Website https://medicine.chm.msu.edu/ Summary of Health Risks This position involves working with chemicals and biohazard level II biologics and mice.