The position calls for a motivated biological scientist to join the Molecular Pharmacology group within the WCNDD. The Pharmacology team is responsible for conducting high-throughput screening assay of small molecule modulators of GPCRs, ion channels, and kinases. This includes development of target protein cell lines and secondary pharmacological assay to support all molecular pharmacology activities. This position is a key contributor to support the Center’s goal of developing therapeutics, specifically for central nervous system disorders. Successful candidates will interface with members among all areas of the WCNDD, including those in molecular pharmacology, medicinal chemistry, drug metabolism and pharmacokinetics, and in vivo rodent pharmacology.  

  Duties and Responsibilities

We are all different, yet we all use our unique contributions to serve patients. The Molecular Pharmacology Research Assistant we seek is a person with these qualifications. 

Perform in vitro pharmacological experiments independently or as a part of team. Conduct cell-based screening assays. Analyze data to determine the efficacy and potency of the compounds using data analysis software. Maintain mammalian cell lines used in the screening assays.  Develop stable cell lines specific to new target proteins. Prepare DNA/RNA and Protein samples and analyze in routine molecular biology assay. Assist with general laboratory operations, including ordering supplies and consumables. Perform other duties as needed; assist lab members with miscellaneous tasks. Understand and follow pharmacological assay protocols applicable to assigned tasks. Maintains accurate databases and experimental notebooks of results. 

 

Qualifications

Bachelor’s or Master’s degree in biology, biochemistry, pharmacology, or related field of study is necessary. 2 years’ laboratory experience employing mammalian cell culture work is necessary. Hands-on experience of plasmid preparation, transfection, and Western Blotting.  Good documentation practices with excellent organization and attention to detail Excellent oral and written communication skills. Proficiency in Microsoft Excel. Self-motivated team player with the ability to thrive in a fast paced, dynamic, multi-disciplinary, matrixed environment.

 

Commitment to Equity, Diversity, and Inclusion

At Vanderbilt University, we are intentional about and assume accountability for fostering advancement and respect for equity, diversity, and inclusion for all students, faculty, and staff. Our commitment to diversity makes us who we are.  We have created a community that celebrates differences and lets individuality thrive. As part of this commitment, we actively value diversity in our workplace and learning environments as we seek to take advantage of the rich backgrounds and abilities of everyone. The diverse voices of Vanderbilt represent an invaluable resource for the University in its efforts to fulfill its mission and strive to be an example of excellence in higher education. 

Vanderbilt University is an equal opportunity, affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran, or any other characteristic protected by law. 

Please note, all candidates selected for an offer of employment are subject to pre-employment background checks, which may include but are not limited to, based on the role for which they have been selected: criminal history, education verification, social media review, motor vehicle records, credit history, and professional license verification.