Research Associate - LCMS - Contract- San Diego, California
Proclinical is seeking an enthusiastic and highly-skilled Research Associate - LCMS to join the Bio-analysis team at an exciting biotech in San Diego.
Primary Responsibilities:
The successful candidate will be supporting the progression of our therapeutic programs by conducting bioanalysis of small molecules, antisense oligonucleotides (ASOs), and proteins for preclinical PK and PK/pharmacodynamic (PD) studies. This role demands a solid understanding of analytical principles, hands-on experience with targeted liquid chromatography (LC)-mass spectrometry (MS), and familiarity with DMPK fundamentals.
Skills & Requirements:
Holds a Bachelor's or Master's degree in Chemistry, Biology, Pharmaceutical Sciences, or related field and 1-3 years of experience in bioanalysis.Possesses direct hands-on experience with bioanalysis and absolute quantitation with LC-MS and can perform basic method troubleshooting and optimization.Has a firm understanding of analytical principles and can use figures of merit to evaluate data quality.Provides clear and timely communication for effective collaboration with cross-functional teams.Has exceptional organizational skills, attention to detail, time management, and the ability to work both independently and as part of a team.Willing to learn new techniques as needed to help support the team.
The Research Associate - LCMS's responsibilities will be:
Conduct bioanalysis of drugs, metabolites, and PD markers in complex biological matrices such as biofluids, tissues, and cells.Perform absolute quantitation on a triple quadrupole LC-MS system and calculations for non-compartmental analysis (NCA).Collaborate with DMPK and pharmacology leads on timeline planning, study prep, and experimental logistics.Collect and record experimental data in an electronic lab notebook, ensuring meticulous documentation, data integrity, traceability, and regulatory compliance; produce readable and functional reports for PK data.Contribute to the development and optimization of experimental techniques and protocols to ensure we deliver high-quality data for decision-making.Monitor consumable inventory and provide basic troubleshooting, maintenance, and performance benchmarking for DMPK LC-MS systems.Collaborate with cross-functional teams, including Institute of Sciences, In Vitro/Vivo Pharmacology, Science Integration, Innovation and Insights, and more to support the development and progression of therapeutic programs.Foster a team culture of continuous improvement, ownership, professional growth, and inclusion.
Preferred Qualifications:
Experience performing bioanalysis on small molecules and proteins is desirable; experience performing bioanalysis on ASOs is highly desirable.Knowledge and experience using R-Studio, or similar platforms, for data analysis is desirable.
If you are having difficulty in applying or if you have any questions, please contact Alexander Bero at a.bero@proclinical.com
Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.
Proclinical Staffing is an equal opportunity employer.
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