Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. You’ll thrive in an environment that supports innovation, is committed to ending racism and supporting diversity, equity and inclusion, and provides the resources you need to succeed.
Benefits Highlights
Medical: Multiple plan options.Dental: Delta Dental or reimbursement account for flexible coverage.Vision: Affordable plan with national network.Pre-Tax Savings: HSA and FSAs for eligible expenses.Retirement: Competitive retirement package to secure your future.
Responsibilities
The Gounari Lab (Dr. Gounari Fotini Bio) explores the molecular processes that govern normal T cell development and the deregulation of these processes in inflammatory diseases and cancer. Our research focuses on the dynamic functions of TCF-1, a context-dependent transcription and epigenetic regulator. TCF-1, a T cell-specific DNA-binding protein, plays multiple stage- and lineage-specific epigenetic roles during T cell development. While TCF-1’s critical roles in T cell biology is well established, significant gaps remain in our understanding of how TCF-1 orchestrates these functions across different developmental stages and cellular contexts.
To address these questions, we have developed novel animal models that allow for auxin-inducible, short-term degradation of TCF-1 in vivo. These models enable us to study the molecular and epigenetic changes—such as chromatin accessibility, 3D chromatin structure, gene expression, and developmental progression—that occur when TCF-1 is acutely depleted and later restored. We are now seeking a highly motivated postdoctoral researcher to join our lab and contribute to this exciting area of research.
Key Responsibilities:
Use our auxin-inducible animal models to study the dynamics of TCF-1 degradation and restoration.Analyze and interpret high-dimensional genomic data.Collaborate with lab members to develop new experimental strategies and methodologies.Publish research findings in top-tier journals and present data at scientific conferences.Interested applicants are required to submit a CV, a brief cover letter describing their research experience and interests and contact information for at least two references.
A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.
Qualifications
Ph.D. in molecular biology, epigenetics, immunology, or a related field.Strong expertise in chromatin accessibility assays, 3D chromatin structure analysis, and gene expression profiling (e.g., RNA-seq).Experience with animal models and/or T cell biology is highly desirable.Strong problem-solving skills, ability to work independently, and interest in collaborative research.Excellent written and oral communication skills.
Exemption Status
Exempt
Compensation Detail
$xx,xxx - $xx,xxx / year; This position has a predetermined rate of $xx.xx per hour.; Education, experience and tenure may be considered along with internal equity when job offers are extended.; $xx.xx - $xx.xx / hour; Compensation range is $xx.xx -$xx.xx / hour based upon union contract
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday through Friday normal business hours.
Weekend Schedule
Occasional weekends to meet the needs of research.
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Affirmative Action and Equal Opportunity Employer
As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.
Recruiter
Lei Feng