At Mass General Brigham, we know it takes a surprising range of talented professionals to advance our mission—from doctors, nurses, business people and tech experts, to dedicated researchers and systems analysts. As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community. We place great value on being a diverse, equitable and inclusive organization as we aim to reflect the diversity of the patients we serve.
At Mass General Brigham, we believe a diverse set of backgrounds and lived experiences makes us stronger by challenging our assumptions with new perspectives that can drive revolutionary discoveries in medical innovations in research and patient care. Therefore, we invite and welcome applicants from traditionally underrepresented groups in healthcare — people of color, people with disabilities, LGBTQ community, and/or gender expansive, first and second-generation immigrants, veterans, and people from different socioeconomic backgrounds – to apply.
Job Summary
A Research Laboratory Technician I position is available in the laboratories of Drs. Murat Bastepe, Harald Jueppner, and Thomas Gardella in the Endocrine Unit at the Massachusetts General Hospital. This is a full-time 40 hour/week position. The primary responsibility is to assist in ongoing research studies under the supervision of Principal Investigators in the Endocrine Unit.The Endocrine Unit is a leader in investigating, diagnosing, and treating disorders of bone and mineral metabolism, parathyroid diseases and general endocrine conditions. Responsibilities include collecting and accurately recording procedures and results, maintaining databases used in the lab, ordering necessary reagents to conduct experiments, and participating in joint upkeep of the lab. This position requires a person who has a Bachelor of Science degree in molecular/cell biology, biochemistry, or a related field, pays attention to details, is capable of working independently under close supervision after initial training, possesses good verbal and written communication skills, and works well as part of a team. Work is reviewed regularly with the Principal Investigators, who is available to troubleshoot problems.
Qualifications
Principal Duties and Responsibilities
Maintains colonies of mice for ongoing projects in the Endocrine Unit. Coordinates matings, performs tagging of mice, genotyping and sequence analysis of genes. Maintains information in databases for mice and coordinates animal transfers.
Responsible for ordering common laboratory reagents and other supplies and for assuring that supply levels in the lab are adequate. Prepares materials for shipping, assuring compliance with regulations for biological samples.
Operates moderately complex equipment including microscopes, centrifuges, autoclave, spectrophotometers, PCR machines, quantitative real-time PCR machines, and the dual-detector Envision.
Techniques used will include: PCR, subcloning, plasmid preparations, maintenance of cell lines, dissection of mice for histological analysis, sectioning of tissue samples, cell culture, Western blotting, immunohistochemistry, RNA analyses.
Imbedding and sectioning of tissue specimen, staining of histological sections.
Organizes and accurately maintains written records of experimental procedures and data collection. Data may be represented as graphs, charts, tables, illustrations, slides and narrative reports. Is able to learn to interpret data results and has a high degree of computer literacy.
Aids in maintaining information in databases for plasmids, cells, antibodies, and primers and boxes in the fridge, -20 and -80 freezers.
Performs basic design and modification of protocols. Executes protocols of non-routine experiments.
Participates in the upkeep of the lab, performs basic maintenance on laboratory equipment (cleans, disassembles, stores, replaces worn parts), and reports equipment requiring advanced repair.
Participates in and presents data at weekly lab meetings and journal clubs.
Interacts well with others and assists in training laboratory personnel in lab techniques and procedures that have been acquired.
Education
BS/BA in biology, molecular biology, biochemistry, or a related field is required.
Experience
Prior laboratory experience, either through academic coursework, internships, or employment. 1-2 years preferred
Knowledge, Skills and Abilities
Experience with basic laboratory techniques in the setting of a research experience or undergraduate biochemistry/molecular biology lab, e.g., sterile cell culture techniques and basic molecular biology techniques–such as plasmid purification, gel electrophoresis, and PCR, generation and staining of histological sections from bone, kidney and possibly other organs. Ability to build upon these techniques, learning new ones as necessary, to conduct the research project.
Analytical skills and the ability to resolve technical problems.
Computer literacy.
Good verbal and written communication skills.
Must be self-motivated and able to work independently.
Additional Job Details (if applicable)
Working Conditions
Duties will be performed onsite at the research laboratory.
Must be willing to work with mice.
Remote Type
Onsite
Work Location
60 Blossom Street
Scheduled Weekly Hours
40
Employee Type
Regular
Work Shift
Day (United States of America)
EEO Statement:
The General Hospital Corporation is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.