Dana-Farber Cancer Institute is seeking a research technician to join the IMmunotherapy Platform for Antibody and CAR Therapeutics discovery and Translation (IMPACT2), a pre-clinical research group with the mission to streamline “discovery to translation” of antibody-based immunotherapies for cancer. The IMPACT team will work closely with DFCI PIs as well as external antibody discovery partners to develop and implement the discovery and functional screening of antibody ‘hits’ as well as the engineering of hits to generate potential therapeutic bispecific T cell engagers and CAR T-cell immunotherapies as well as other antibody therapeutic formats. The candidate should be motivated to learn and execute workflows for producing, screening, and characterizing the biochemistry and in vitro function of candidate antibody and CAR T cell therapies.
We are deeply committed to the success of each trainee that joins the lab and believe that mentorship should be intentional, thought out, and personalized for each member of the group. We dedicate time to meet trainees' individual needs for scientific growth and pursuit of their career goals.
We are seeking candidates with at least two years of availability.
The Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Responsibilities Execute biochemical, molecular and/or cell biology experiments, contributing to production, purification and binding/functional characterization of monospecific and multi-specific antibodies.Execute workflows for producing and functionally screening CARs and antibodies to identify leads for ultimate clinical translation. Analyze experimental data and interpret results. Write reports and summaries of findings. Participate in formal and informal presentations of results. Maintain detailed electronic notebook, carefully document samples, methods and observations.Development, improvement and adherence to standard operating procedures.Proactive and reliable stewardship of the laboratory. Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.Maintain, clean and prepare supplies and work areas. Ensuring supplies are ordered for the group.Intellectual commitment to position by keeping up with appropriate literature and actively participate in lab meetings, journal club and research seminars.Intellectual input and co-authorship are encouraged. Qualifications B.S. degree or M.S. in a relevant field (i.e. Biology, Bioengineering or Chemical Engineering, etc.) with experience in molecular, protein or cell biology. Research lab experience in a full-time research lab (academic or biotech/pharma) is required. Learns and uses technical principles, processes, and concepts. Exceptionally self-motivated, dedicated, and reliable.Follows standard practices and procedures Builds stable working relationships, able to work with a wide range of faculty and staff.Excellent written and verbal communication skills.Outstanding planning, organizational and multi-tasking skills.Must have attention to detail and be thorough in completing work tasks.
Only applicants that submit a cover letter and a detailed CV will be considered. Cover letter should not be a reiteration of your CV, but focus on interests and career goals. Following a pre-screen interview, candidate will be requested to provide the contact information for three references.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
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