**Job Title:** RNA Bioinformatics Summer 2025 Intern - Vaccine **Location:** Waltham, MA **About the Job** At Sanofi, we chase the miracles of science, and we know mRNA has a role to play in the future of health. And while the pandemic has shaken up our industry, creating new opportunities and risks, we believe the acceleration of innovation with mRNA technology means vaccines and treatments for more people faster than before. That’s why we’re looking for bold, optimistic world-changers to join our mRNA Center of Excellence. We’re investing €400m a year into the new Center, hiring a team of 450 dedicated employees, and focusing on implementing an integrated end-to-end mRNA vaccine capabilities and research with R&D, digital and CMC teams. Bring your ambition and optimism and join us on our journey to discover and deliver transformative medicine to patients through the advancement of our cutting-edge mRNA technology! As an RNA Bioinformatics Intern, you will participate in a 4-month summer internship project in the areas of cheminformatics, bioinformatics, computational biology, and machine learning to the task of developing and implementing first-in-class and best-in-class computational solutions and models for screening, optimizing and evaluating lipid nanoparticles or RNA molecules for mRNA-based vaccines and therapeutics as part of the Data and Computational Science team in the mRNA CoE. This team brings end-to-end data integration and advanced analytics (pre-clinical, biomarkers, process development, CMC, clinical) in the mRNA CoE. Deploying and exploiting digital solutions (AI/machine learning, data, analytics) to integrate the full data value chain, extracting actionable information for a move to a full data driven strategy and decision-making process, to increase probability of success and to accelerate mRNA vaccines and therapeutics development and launch. We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world. **Main Responsibilities:** + Collaborate with group experts in the development and execution of the scientific strategy and technical solutions to develop best-in-class mRNA vaccines and therapeutics + Execute development of a project to deliver data and computational solutions for the integration of chemical, structural, and biological data to support data analytics and visualization + Collaborate internally to develop scientific hypotheses and drive new scientific insights based on computational frameworks + Develop computational pipelines (e.g., with Nextflow, Snakemake, or WDL) for a variety of Research and Development applications, with particular focus on in vitro and in vivo mRNA screening assays; next-generation sequencing (NGS) data and analysis; and the design, assembly, and quality control (QC) of pDNA and mRNA vaccines and therapeutics + Create compelling visual representations of data and analytics results in support of presentation, communication, and decision-making needs for key stakeholders + Provide support for experimental results using data analytic and/or machine learning techniques + Maintain a well-documented, reusable codebase, and traceable model history + Maintain awareness of latest developments in relevant fields, evaluate and apply as warranted + Demonstrate good software engineering practices + Proactively identify, assess, and internalize emerging technologies and methods **About you:** ****At this time, Sanofi will not sponsor a new applicant for employment authorization or offer any immigration related support for this position (i.e. H1B, F-1 OPT, F-1 STEM OPT, F-1 CPT, J-1, TN, or another type of work authorization). **** **Basic Qualifications:** + Currently pursuing a PhD or master's degree in Cheminformatics, Bioinformatics, Computational Chemistry, Computational Biology, Computer science, or related quantitative disciplines at an accredited college or university with the expectation that you will complete your current degree by the Spring of 2027 + Must be enrolled in school the semester following your internship/co-op with Sanofi + Must be able to relocate to the office location and work 40hrs/week, Monday-Friday, for the full duration of the co-op/internship + Must have permanent US work authorization **Preferred Qualifications** : + Have a basic understanding of different types of NGS assays + Experience with NGS data/statistical analysis, with a preference for topics such as exploratory analysis and -omics data (e.g., ribosome profiling) + Experience with machine learning, such as development of regression/classification models and deep learning models, is preferred but not required + Familiarity with cloud and parallel computing + Comfortable with one or more common data analysis and visualization platforms (e.g., R, RShiny, Python/pandas) and bioinformatics packages (Bioconductor, Biopython, etc.) + Comfortable engaging with stakeholders from a variety of backgrounds and working collaboratively towards a common goal + Adept at communication and adaptation + Willing to train individuals and teams on your areas of expertise and on systems you build + Fluency in English; Fluency in French is a plus **Why Choose Us?** + Bring the miracles of science to life alongside a supportive, future-focused team. + Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. + Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. + Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. \#GD-SP ​ \#LI-SP \#LI Onsite \#vhd \#mRNA **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! _US and Puerto Rico Residents Only_ Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)