RNA-Delivered Antibody-Based Therapy Engineering and Screening – Scientist I
Pre-clinical group developing next generation antibody and CAR T cell immunotherapies for cancer is looking for an exceptionally motivated individual with past lab experience. The group takes projects from conception to transgene design /genetic engineering, through reduction to practice, in vitro and in vivo studies, and ultimately to the clinic. The candidate will make substantial contributions to the planning, execution, and data analysis and should have prior experience with RNA and/or protein engineering. We expect a strong background in some of the laboratory methods required to perform this bench work and we provide training to expand the scientist’s took box. Additional opportunities for growth are attending lectures and journal clubs held here at DFCI and participating in academic and industry collaborations. The work is highly translational and there is a clear path to moving to the clinic a candidate based on this work.
Located in Boston and the surrounding communities, The Dana-Farber Cancer Institute brings together world-renowned clinicians, innovative researchers and dedicated professionals, allied in the common mission of conquering cancer. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to all patients; we conduct research that advances treatment; we educate tomorrow’s physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
We are looking for an enthusiastic, self-motivated, independent thinker with a tremendous work ethic. The position will require great planning and organizational skills. An ability to work well with others as part of a cohesive team, take initiative, and creatively problem solve are a must.
ResponsibilitiesDesign and perform experiments both individually and collaboratively.Analyze experimental data and interpret results.Maintain detailed electronic notebook of all experiments.Exercise judgment in selecting methods, techniques and evaluation criteria for obtaining results.Generate data of a quality upon which decisions for the future direction of a program can be based.Write reports and summaries of findings.Participate in formal and information presentations.Keep up with appropriate literature and research publications.Develop, modify and improve of laboratory procedures.Contribute to technical reports, the grant application process and manuscript preparation as required.Operation and maintenance of lab equipment as requiredProactively contribute to the smooth running of the laboratory May direct work and be involved in training of junior staffCollaborate and coordinate with team members across groups and functions
Qualifications
PhD or equivalent. Masters with substantial experience in protein or RNA biochemistry will be considered.Prior experience with antibody/protein engineering and/or RNA-therapies.We are seeking candidates with at least 2 years of availability.Exceptionally self-motivated and eager to expand existing skill.Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.Outstanding organization; and is detail oriented.Must consider attention to detail a strength.Outstanding planning, organizational, multi-tasking skills.Ability to work within a team environment.
Only applicants that submit a cover letter, detailed CV will be considered.
As part of the selection process the contact information for three references will be requested.
Faculty Director: Eric Smith, MD PhD (https://ericsmithlab.dana-farber.org/).
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.
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