HD Biosciences Inc., a WuXi AppTec company, offers biology-focused preclinical drug discovery services to biotech and pharmaceuticals. We offer our clients comprehensive service platforms around target validation, plate-based pharmacology, hit identification and lead discovery, in vivo pharmacology, as well as other research and development services.
We are seeking a highly motivated and skilled scientist to join our fast-growing bioanalysis team. The position will independently design, execute, trouble shoot and deliver the projects with LCMS, including small molecules and biologics.
Responsibilities• Provides scientific and operational support for bioanalysis group.
• Actively contributes and applies expertise and knowledge to collaborations with partners in the design and execution of related studies
• Contributes to project proposal preparation.
• Leads ongoing projects to meet expected timelines.
• Contributes for new capability implementation and team building.
• Contributes to the overall operations and to the achievement of departmental goals
• Communicates with clients for designing, analysis, reporting and recording activities.
• Performs job specific tasks in compliance with applicable Regulations, International Standards, WuXi AppTec Policies and Standard Operating Procedures.
• Hands-on bench work when necessary.
• PhD with 0-2 years of experience, MS with 3+ years of experience in Proteomics, Mass Spectrometry, and/or related field.
• Strong scientific knowledge and technical skills in the bioanalytic field is desired; Industry experience is a plus.
• Expert level skills in the following areas are required:
o Solid understanding of qualitative and quantitative LC-MS workflows in small molecule, biologics, and proteomics with associated sample preparation techniques.
o Solid competency in a broad range of LC-MS instrumentation such as QQQ, QTOF and orbitrap and application solutions, and related method development and validation.
o Experience with sample preparation from tissues, cells, and biofluids as needed to enable quantitative workflows for drug discovery programs.
o Experience in protein characterization, peptide mapping, PTM analysis and targeted proteomics.
o Experience in DMPK/Bioanalysis
o Experience with MaxQuant, Skyline and Tracefinder, Protein Pilot, Proteome Discoverer.
o Must be able to maintain UPLC/Mass spec for routine operations.
o Prior in vitro assays and in vivo pharmacology experience is a plus.
Knowledge / Skills / Abilities:
• Demonstrated time management and multi-tasking skills, ability to effectively prioritize workload and manage changes in direction.
• Demonstrated ability for attention to details and concern for impact.
• Effective communication skills with the ability to give and receive feedback, both verbally and in writing.
• Ability to work in a team environment and independently as required.
• Ability to work in a fast-paced environment.
• Well organized and adaptable to changes.
• Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint. Ability to learn instrument and data analysis software.
Anticipated base pay range: $64,770 to $84,150
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability
This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.
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