Job Title: Scientist III Location: Ridgefield, CT Type: Contract Responsibilities + Strong scientific understanding and experience in bioinformatics analysis and their implications in disease biology + Working knowledge of NGS based omics data analysis (bulk and single cell RNA-seq, spatial transcriptomics analysis is a plus) + Identify and process publicly available and internal generated bulk, single-cell and spatial transcriptome datasets using statistical and bioinformatics techniques to create meaningful biological insights + Apply and develop innovative analysis approaches when standard methods are not adequate + Follow relevant scientific literature to ensure use of optimal methods and understand emerging practices across the field + Interpret and present analysis results to coworkers, biologists and collaborators. Communicate work effectively orally and in writing + Ensure FAIR data analysis with clear documentation and reproducibility + Report and treat data with a high level of integrity and ethics + Comply with applicable regulations; Maintain proper records in accordance with SOPs and policies Requirements + Programming experience with two or more programming languages including: Python, R for bioinformatic data analysis, shell/bash programming in unix-like systems. + Proficiency in working with bulk and single cell NGS data, spatial transcriptomic data analysis is a plus + Proficiency in working with cloud computing and high performing clusters (HPC) + Experience in biological pathway analysis + Experience in applying machine learning and artificial intelligence methods to biological data, deep learning and graph learning is a plus + Two years hand on experience of bioinformatic data analysis + Solid background in basic biology and disease biology. Knowledge in oncology or immunology is a plus. + Ability to develop and benchmark machine learning algorithms + Experience in using common public oncology datasets is a plus (TCGA, GTEX, Human cell atlas, CZ CELLxGene Discover, Human tumor atlas network, etc) Education: + PhD/Master’s degree from an accredited institution with experience in a related scientific discipline (Computational Biology, Genomics, Biostatistics, Bioinformatics and Biological Sciences preferred) Benefits System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan. System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan. System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.