Site Name: Belgium-Rixensart, Belgium-Wavre Posted Date: Dec 3 2024 As a Scientist in the Size & Morphology Platform, you will have a unique opportunity to work in a dynamic, multidisciplinary team within the Global Physical and Chemical organisation of Vaccine CMC Analytical and Statistics R&D. Your role will involve the characterisation and release of vaccine candidates using a variety of technologies, including sized-based and imaging-based techniques such as DLS, SLS, NanoFCM, SEC, MALLS and Cryo-EM, SEM, confocal microscopy. This includes analytical method development according to Quality by Design principles, from early vaccine candidates up to validation for Phase III programs and working in a regulated environment related to the testing of Clinical Trial Material. Your responsibilities: · You will be responsible for designing, developing and hands-on application of state-of-the-art techniques to characterise mRNA vaccine candidates (oligo/polynucleotides and LNPs, regarding size, structure, morphology, integrity, encapsulation, etc.), and providing fit-for-purpose analytical methods in interaction with Analytical Product Leaders & Sub teams (APL & AST), as well as Industrialization Leaders (AIL). · You will be involved in and presenting during GMP/Non-GMP quality and EHS audits. · You will interpret and report results after an extensive check of the raw data quality and critical results analysis. · You will be deeply involved in generating appropriate analytical documentation for method development up to qualification and validation. · You will present results to the appropriate stakeholders within ARD and beyond. · You will interact with other Technical R&D (TRD) departments (Drug Substance, Drug Product, Statistics team), Preclinical, Regulatory, and GIO/QC organizations. · You will ensure scientific/technology watch in your competency domain and will interact with external experts and equipment providers to ensure adequate implementation of technological innovation. · You will plan and execute activities in the laboratory in collaboration with technicians and other team scientists located at the Rixensart and Wavre sites. · You will provide support, technical advice and coaching to technicians and scientists. · You will participate in lab organization and maintenance, e.g., ordering reagents and consumables and following up on instrument maintenance and repair in collaboration with the lab support team. Why you? The Required Qualifications: We are looking for professionals with the following required skills: · Master's or PhD degree in Chemistry, Biochemistry, Biophysics, Biology, Bioengineering, Chemical Engineering, Pharmacy (or other relevant discipline), or equivalent demonstrated experience. · A minimum of 2 years of experience in a similar position. · Good working knowledge of Quality by Design principles. · The platform covers diverse analytical technologies. Demonstrated expertise, including hands-on experience in some of these technologies, and awareness of all of them are essential. · Ability to lead method development, qualification, and validation projects within the area of expertise. · Sound scientific methodology and thinking, autonomy, commitment to solving problems and bringing innovative solutions to the team. · Communication skills (oral & writing), ability to engage the team and stakeholders; open-minded, result- and quality-oriented; networking. · The native language of the team is French; however, English fluency is a must. If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology). Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. 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