**Join Amgen’s Mission of Serving Patients** At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. **Senior Associate- In Vitro Neurobiology** **What you will do** Let’s do this. Let’s change the world. Amgen’s cardiometabolic team is an innovative target discovery and translational research unit with a focus on identifying novel targets for development of game-changing therapies for patients with obesity and associated cardiometabolic diseases. We employ advanced computational biology, state-of-the-art discovery screening technologies, genetics, and human-centric cell systems to dissect pathophysiology and identify novel drug targets. This laboratory-based position will focus on cell culture support for the development of large-scale qualitative and quantitative functional genomics screens utilizing human derived central nervous system (CNS) models. There is an overarching aim to characterize genes and genetic regulatory circuits involved in the control of cellular metabolism and advance discovery projects by performing in vitro experiments under partial supervision. **Essential Functions:** + Work in an in vitro setting using aseptic technique, passaging, expansion, cryopreservation, assessment of cell-line quality, and cell characterization + Maintain mammalian cell cultures derived from iPSC and/or primary neuronal or glial models + Utilize functional cell-based assays and support in the development of: immunoassays (western blot, ELISA, flow cytometry, immunofluorescence staining), fluorescent microscopy, and other imaging methods + Operate and maintain standard lab equipment + Document experimental plans and procedures timely with attention to detail + Exhibit self-motivation and proactive attitude in designing and conducting experiments using state-of-the-art technologies + With some supervision, plan, conduct or monitor experiments, record and organize data, analyze results, troubleshoot, and generate robust and reliable data **What we expect of you** We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a collaborator with these qualifications. **Basic Qualifications:** Master’s degree **Or** Bachelor’s degree and 2 years of related scientific experience **Or** Associate’s degree and 4 years of related scientific experience **Or** High school diploma / GED and 6 years of related scientific experience **Preferred Qualifications:** + At least 2 years of mammalian cell culturing experience + Demonstrated experience using assay technologies (e.g., luminescence, fluorescence, TR-FRET, AlphaLISA or high-content systems). + Experience performing molecular biology experiments (such as RNA, DNA extraction, qPCR, cloning, CRISPR/Cas9-based genome editing) or performing antibody-based experiments (flow cytometry, ELISA, immunofluorescence imaging and western blot). + Hands-on experience in handling samples in 96-well format is preferred + Familiarity with metabolic disease biology, particularly in obesity or related fields + Strong organizational, analytical, and problem-solving skills + Proficiency in GraphPad Prism, Microsoft Word, Excel, and PowerPoint **What you can expect of us** As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: + A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts + A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan + Stock-based long-term incentives + Award-winning time-off plans + Flexible work models, including remote and hybrid work arrangements, where possible **Apply now** **for a career that defies imagination** Objects in your future are closer than they appear. Join us. **careers.amgen.com** In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. **Application deadline** Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.