**Working with Us** Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. The Immunology and Cardiovascular (ICV) Thematic Research Center (TRC) at BMS is one of the fundamental Research and Early Development (R&ED) units delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow based on the cutting-edge science of today. We leverage BMS's internal innovation engine that includes industry-leading expertise in small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and other therapeutic modalities. We work closely with our R&ED colleagues in clinical and non-clinical development, project leadership, translational medicine, and informatics to advance therapies based on a deep understanding of causal human biology. Furthermore, we collaborate across the biopharmaceutical ecosystem to establish partnerships that complement our internal expertise. **Position Summary** Bristol-Myers Squibb's newest R&ED site located in Cambridge is in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities. We are seeking a skilled and motivated scientist with experience in various aspects of immunology, viral immunity, molecular biology, and drug discovery. This person will focus on drug discovery within the area of autoimmune and inflammatory diseases, which includes (but not necessarily limited to) target identification, target validation, elucidating drug mechanism of action, molecular basis of disease states, and the assessment/development of novel modalities for use in drug discovery. The desired candidate will be well-versed in various biochemical, cellular, and immunological techniques in the laboratory, but also have an insatiable curiosity to lead them towards continually expanding their scientific repertoire. This individual will demonstrate sophisticated scientific thinking and have the capacity/eagerness to rise to challenges. A strong work ethic, good judgement, and the ability to work equally well in a team or independently are key qualities in the successful candidate. **Key Responsibilities** + Design, develop and execute in vitro/ex vivo experiments based on literature discoveries, in vitro experimental data, in vivo animal modeling, immunological evolution, genetics, clinical data, and technological advances. + Collaborate alongside a cross-functional team that includes immunologists, chemists, computational chemists, biochemists, in vivo biologists and proteomics experts to discover new targets, derive new biological mechanistic insights, and support programs as they move through clinical development. + Execute primary cell-based (mouse, monkey and human), whole blood, and cell line-based experiments such as ELISAs, genetic manipulations, western blots, immunofluorescence, flow cytometry, immunoprecipitation, qPCR, RNA-seq, etc. to drive early discovery efforts. + Design sophisticated cross-disciplinary experiments within project teams to enable the progression of therapeutic candidates through the drug pipeline. + Innovate + Excellent communication, record keeping, presentation, collaboration and organizational skills are required. + Travel will be less than 5% of the time. **Basic Qualifications:** + Bachelor's Degree + 4+ years of academic and / or industry experience Or + Master's Degree + 2+ years of academic and / or industry experience **Preferred Qualifications:** + Research experience in inflammatory & autoimmune diseases, molecular immunology, immunometabolism, infectious diseases, neuroimmunology and/or cancer immunotherapy is required. + Extensive hands-on experience in tissue culture handling of primary immune cells from human/animal tissues is required. + Experience with viral infection of cell-lines and primary cells is required. + A clear track record of scientific accomplishment and a natural self-starter. + A sophisticated understanding of experimental design and the ability to identify scientific problems as well as potential solutions. + Evidence of sustained independent thought as well as creativity in developing unique scientific ideas/technologies. + An ability to analyze large multi-dimensional (e.g. multi-OMICs) datasets is desired, but not required. **Why You Should Apply** Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. **Uniquely Interesting Work, Life-changing Careers** With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. **On-site Protocol** BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. **Company:** Bristol-Myers Squibb **Req Number:** R1584778 **Updated:** 2024-11-13 03:12:21.962 UTC **Location:** Cambridge Crossing-MA Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.