**Working with Us** Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us . **Drug Product Development (DPD)** Our Drug Product Development team is committed to CMC design, development, and commercialization of innovative drug products to improve patient lives. We leverage the best people, collaboration, and cutting-edge innovation to achieve this commitment. BMS's internal engine of innovation includes unrivaled industry leading expertise in CMC development of small molecules, protein biotherapeutics, protein degraders, and other therapeutic modalities. We collaborate closely with our colleagues in R&D and Commercial to design our drug products. Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. **Position Summary:** The Device, Delivery and Product Strategy team within the Global Product Development and Supply organization supports the BMS pipeline to create patient centric products . We now have a vacancy for a Senior Principal Engineer to join our team and contribute to our success in meeting the needs of our business and our patients. The Senior Principal Engineer is a n important role in advancing modeling strategies and innovative methods generating valuable insights using internal and external data sources. In this role, you will provide technical leadership through mechanistic modeling, model based DOEs, and material science. With the modeling first mindset, the successful candidate will design and develop predictive models for device delivery systems, powder-, fluid-, & polymer-based systems and multiphase flows in drug product development and manufacturing. This work will advance the field of predictive design in the pharmaceutical industry as well as enhance the understanding of product development. The selected candidate will work in a fast-paced multidisciplinary environment as the competitive landscape and modeling strategies keep changing rapidly. The **Senior** **Principal** **Engineer** will be accountable for the following: + Generating, leading modeling and digitization initiatives for device and combination product development including digital twin s of products and processes, product and process modeling, multiphysics modeling etc . + Execution of design and development activities, such as concept generation, CAD design, prototyping and testing. + Compliance with company processes and procedures. **Qualifications:** + PhD in M echanical Engineering or related engineering discipline with 6-8 years of experience or MS with 9-12 years of experience in the Medical Device, Pharmaceutical , Biotechnology or other industry with an emphasis on product and process modeling . + Research experience in the field of engineering and computational modeling techniques is required (e.g., Bayesian models, finite element or discrete element modeling, computational fluid dynamics CFD, flowsheet modeling, and first- principle s engineering models) + Deep understanding of multi-physics interactions, design for manufacturing and assembly." Design for environment would be a plus. + Advanced knowledge of software such as SolidWorks, ProE , Abaqus, HEEDS, COMSOL, MoldFlow , Fluent etc. + Ability to convert models into experiments, w ork autonomousl y and partner with the modelling community across Product Development . + Ability to build and manage models to predict future outcomes using data that is often incomplete and/or imperfect and contained in disparate source + Deep understanding of complex mechanical engineering design & simulation demonstrated by past experience developing such products. + Strong cross-functional leadership skills and ability to lead and influence matrix teams . + Demonst rated ability to work as part of internal teams and also leverage external partners to bring the right technologies into products. + Strong written and verbal communication skills, with the ability to communicate complex technical information to a non-specialist audience. Detail oriented with strong documentation skills + Ability to survey external competitive landscape, industry trends, and regulatory environment as it pertains to our areas of interest and the BMS portfolio . + Experience with data visualization (e.g. R, DASH, Spotfire, Tableau) and statistical tools and models (e.gs. PCA, ANOVA, Minitab, JMP), p roficiency in Python (or other scientific programming languages) to curate and analyze historical and data at scale and to implement new metrics is a nice to have. + Ability to perform in-depth data analysis and present results and conclusions to product development and leadership teams **Preferred/Desired skills:** + Examples of your work, such as GitHub repository or publications that can showcase your skill + Experience working in a cloud environment and using cloud-based services is desirable + Experience with Jupyter Notebooks and/or Shiny applications is a plus + Proficient in fundamental engineering/physical concepts such as mass, momentum, and energy transport phenomenon; and a mathematical ability to setup and solve linear, non-linear, and differential equations. If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. **Uniquely Interesting Work, Life-changing Careers** With a single vision as inspiring as Transforming patients' lives through science™ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. **On-site Protocol** BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ (https://careers.bms.com/eeo-accessibility) eeo-accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. **Company:** Bristol-Myers Squibb **Req Number:** R1586772 **Updated:** 2024-11-13 03:12:21.349 UTC **Location:** New Brunswick-NJ Bristol Myers Squibb is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law.