Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We are pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs.  With five currently marketed medicines for serious diseases and an expansive late-stage pipeline, we continue to build upon our groundbreaking innovations in science and technology to provide greater value to patients; and we are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know our success is a direct result of the exceptional talent and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money, and energy into making our onsite and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We are building on our rich history, and believe our greatest achievements are ahead of us.  We invite you to apply and join us if you’re passionate about the opportunity to have meaningful impact on patients in need, our employees, and our organization.  Experience and contribute to our unique culture while you develop and expand your career!

 

SENIOR SCIENTIST, BIOMARKERS

 

SUMMARY:

We are seeking a highly motivated and outstanding individual to join our Biomarkers group as a Senior Scientist. The Biomarker group develops, supports, and implements the biomarker strategy to support the wholly owned Ionis pipeline. This is a new position that is an individual contributor on the team. This individual will be working with cross-functional teams to devise, support, and provide scientific input on the development and implementation of the Biomarker strategy for individual programs. They will be responsible for the biomarker research plans for assigned programs and will support experimental design, data interpretation, and overall scientific needs. They will lead a cross-functional team for each project, interfacing with research, clinical development, and the biomarker bioanalytical lead. Additionally, they will be responsible for designing and conducting experiments in the laboratory to support biomarker research activities. The candidate must have scientific experience, with strong critical thinking and project leadership skills.

RESPONSIBILITIES: 

Responsible for working with Research and Clinical Development leads, and within the Biomarker group, to devise and execute the biomarker strategy with excellence for assigned programs Support and provide scientific input on biomarker activities (preclinical studies, clinical data interpretation, regulatory strategy) Independently lead/provide oversight of biomarker research activities: Biomarker biology/dynamics Support biomarker bioanalytical activities Lead biomarker meetings and provide regular updates to key stakeholders Communicate in an effective and timely manner with team members and senior management regarding project status, timelines, milestones, key events, and changes to the biomarker strategy Design and conduct experiments to identify biomarkers, evaluate feasibility of new methods, and support the understanding of biomarker dynamics/biology (10-30% of role) Represent Biomarkers in research meetings and be readily available to advise on biomarker related updates and questions

REQUIREMENTS:

PhD in biochemistry, molecular biology or a related field with postdoc or 2+ years of industry experience Degree and/or background working on neurological diseases would be a plus Critical-thinking and problem-solving skills with attention to detail. Experience devising, designing, and executing scientific experiments and projects Expected experience includes running protein and RNA assays, including ELISAs, Western blots, and qRT-PCR The following experience would be beneficial but is not essential: Experience with assay development Running assays such as targeted RNA-seq or mass spectrometry Ability to multi-task and manage several projects in parallel. Work collaboratively and productively in fast-paced cross-functional teams. Excellent communicator who is comfortable leading and presenting in cross-functional meetings and maintaining open and effective lines of dialogue, addressing problems and collaborating constructively with team members Must be organized, adaptive, and detail oriented, with the ability to multitask, and manage multiple programs in parallel with competing priorities Proven ability of being productive and successful in an intense work environment Candidate must be in San Diego or willing to relocate (fully onsite or hybrid) Travel minimal 0-10%

 

Please visit our website, www.ionis.com for more information about Ionis and to apply for this position; reference requisition #IONIS003434

Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits

Full Benefits Link: https://www.ionis.com/careers/working-at-ionis/#:~:text=to%20Applicants%C2%A0%C2%BB-,Benefits,-Employees%20are%20rewarded

The pay scale for this position is $105,000 to $145,000

NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.