Cambridge, MA, 02238, USA
7 days ago
Senior Scientist, Flow Cytometry and Imaging Applications
Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok (https://www.tiktok.com/@abbvie) . Job Description We are seeking a scientist responsible for performing flow cytometry and high content imaging in Neuroscience Drug Discovery. This will be a highly collaborative role, with opportunities to work on multiple projects across AbbVie as well as external collaborations. Key Responsibilities + Contribute to matrixed teams by supporting flow cytometry and flow sorting experiments in collaboration with neuroscience colleagues. This includes FACS of nuclei from mouse and human postmortem brain, generation of new cell lines based on fluorescent markers, and FACS for pooled whole-genome CRISPR screening. + Operate and work with field service engineers to maintain flow cytometry and sorting equipment. + Operate and work with field service engineers to maintain high content imaging equipment. + High-content imaging data management, provide guidance to colleagues on imaging experiment design, execution, and analysis. + Generate, analyze, and present reproducible data and participate in the interpretation of results. Maintain well-organized records. + Read and apply relevant scientific literature. + Develop scientific and technical proficiency as necessary for project completion. + Contribute to writing of publications, presentations, and patents. Qualifications + Bachelor’s Degree or equivalent education and 10 years of experience; or Master’s Degree or equivalent education and 8 years of experience; or completion of PhD. + Experience with flow cytometry or flow sorting. + Experience with immunocytochemistry and fluorescence microscopy. + Ability to lift 20 lbs. + Experience in cell/molecular biology techniques such as cell culture, immunofluorescence, Western blotting, qPCR, transfection/transduction. + Demonstrated ability to independently design and execute experiments, interpret data, and identify appropriate follow-up strategies. + Proven track record of teamwork, adaptability, initiative, and scientific integrity. + Strong organizational skills that facilitate planning, multitasking and working within timelines. + Record of publications in peer-reviewed journal(s) Preferred Qualifications + Strong experience in hands-on use of flow cytometry and flow sorting instruments; analysis of flow cytometry data. + 2+ years experience in high content imaging and automation in biotech/pharmaceutical company environment, with hands-on experience in small-molecule/genetic-based phenotypic screens. + Strong scientific background in: neuroscience of neurodegeneration, migraine, psychiatry, and the molecular and cellular drivers of disease. Key Leadership Competencies + Builds strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performance. + Learns fast and can change course quickly where indicated. + Raises the bar and is never satisfied with the status quo. + Creates a learning environment, open to suggestions and experimentation to drive the science in the field of interest. + Embraces the ideas of others, nurtures innovation and manages innovation to reality. Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​ + The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​ + We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​ + This job is eligible to participate in our short-term incentive programs. ​ Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​ ​ AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html Salary: $91,500 - $173,500
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