At AstraZeneca's Oncology R&D division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world. We are committed to making a difference and have built our business around our passion for science. Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs.

Position Summary

The Senior Scientist supports Neogene’s efforts in developing TCR-based immunotherapies for solid tumors within the Translational Sciences group. Your work will support data quality control and analysis for clinical sample processing. You will be based onsite in Santa Monica, CA and report to a Senior Scientist.

Responsibilities

Analyze clinical biospecimen data with a focus on complex flow cytometry datasets and reporting of results in the form of presentations or written reports.

Develop data-driven insights to support Translational correlative analyses and implementation of future assays and processes.

Perform and accurate peer data audits and monitor data quality, in compliance with in-house and regulatory standards across multiple clinical programs.

Collaborate with other Translational team members to ensure seamless data flow and enforce reporting to address any discrepancies.

Review and author SOPs, qualification reports, and other related documents.

Analyze, organize, and communicate results at different research meetings. Participate in project teams and work to ensure understanding. Other responsibilities as assigned.

Education and Experience

Bachelor's degree with minimum of 7 years' experience or Master's degree with 4 years with a degree in immunology, cellular or tumor biology or in a relevant discipline with related lab or industry experience.

Background in immunology and immunotherapy.

Well-versed in cell culture aseptic techniques, multi-color flow cytometry (10+ colors), PCR, MSD/ELISA, and other cellular assays. Experience with spectral flow cytometry is a plus.

Familiarity with working with large datasets and with associated data analysis and visualization software (i.e. Cytobank/OMIQ/FCS Express, Tableau/Spotfire/JMP) is a plus.

Will accept temporary responsibilities outside of initial job description.

You will work with biological and/or chemical hazards.

The annual base salary for this position ranges from $108,757 to $163,136. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

#LI-Onsite

Date Posted

14-Nov-2024

Closing Date

14-Dec-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.