_Le contenu du poste est libellé en anglais car il nécessite de nombreuses interactions avec nos filiales à l’international, l'anglais étant la langue de travail._ _This job offer is accessible to all, regardless of gender._ **Job title** **:** _Senior Scientist DP Development_ **_About the job_** **In the race for the future of health – The Sanofi mRNA Center of Excellence (CoE)** At Sanofi, we chase the miracles of science, and we know mRNA has a role to play in the future of health. And while the pandemic has shaken up our industry, creating new opportunities and risks, we believe the acceleration of innovation with mRNA technology means vaccines and treatments for more people faster than before. That’s why we’re looking for bold, optimistic world-changers to join our mRNA Center of Excellence. We’re investing €400m a year into the new Center, hiring a team of 450 dedicated employees, and focusing on implementing an integrated end-to-end mRNA vaccine capabilities and research with R&D, digital and CMC teams. Bring your ambition and optimism and join us on our journey to discover and deliver transformative medicine to patients through the advancement of our cutting-edge mRNA technology! **Our Team** The mRNA – **Senior** **Scientist Drug Product Development** is part of the Global Drug Product Development (GDPD) group within the mRNA CoE. GDPD is responsible for developing the Drug Product formulation and manufacturing process in support of all ongoing mRNA Vaccine programs within the CoE from Phase 1 through Phase 3 and commercialization. GDPD achieves this through internal collaborations with our colleagues in US and through constant collaboration with other departments including Drug Substance Development, Analytical Sciences, Research, Process Industrialization, Global Process Harmonization & Tech Transfer, and cGMP Strategic Supply & Operations. GDPD’s mission is to develop safe, stable, and patient-centric mRNA vaccine and therapeutic Drug Products and associated robust manufacturing processes. **Main responsibilities:** + Apply scientific expertise and judgment to initiate, design and execute orsupervise executionof the development of liquid and lyophilized mRNA-LNP drug productformulation and process + Make scientific presentations and report project progress within mRNA CoE Formulation teams and with partners and in international forums + As a Subject Matter Expert in drug product development, be an impactful contributor to project teams and actively participatein DP sub-teams + Provide consolidated DP development technical work packages with timelines, resources and critical path activities + Drive organizational goal of rapidly incorporating innovative advances in drug product platform (thermostable formulations and process improvements) + Promote innovation, state of the art technologies, and propose strategies using publications to improve the products + Proactively collaborate with other functions to meet projects and platform milestones + Proactively collaborate with other groups or sites in transfer of information, materials anddrugproduct technology + Promote internal assessment of new DP technologies and scientific network to leverage internal and external expertise + Make decisions that require developing new options to solve moderately complex problems + Demonstrate continuous growth in depth and breadth of personal scientific knowledge andunderstanding of strategic goals of group, team, and company + Maintain a consistent record of publications, patents, external presentations + Proactively participate in laboratory organization(including HSE, quality aspects) and continuous improvement of WoW + Supervise lab activities with technicians, internships and TPW (indirect report), when appropriate **About your development opportunities** In this role, you will gain a technical understanding of mRNA vaccine drug product development, drug product characterization techniques, and process development study design strategies. You will be exposed to, and gain an understanding of, what other technical function are responsible for and how they all play a role in mRNA vaccine development. You will have the opportunity to collaborate and learn from management within GDPD as well as other departments. **_About you_** + **Experience** **:** Experience in CMC activities and project management, parenteral drug product development and industrialization required. Understanding of complex R&D landscapes globally, ability to identify cutting-edge technologies and new directions, strong academic and biotech/pharma scientific networks + **Soft skills** **:** Good oral communication, proactive, organized, passionate about scientific progression, leadership, and interpersonal skills. Ability to work in a fast-paced environment + **Technical skills** **:** Formulation, Physical-chemistry of nanoparticles and associated characterization methods, pharmaceutical engineering, knowledge on different unit operations of drug product manufacturing (Lipid Nanoparticles manufacturing, TFF, Freeze/Thaw, mixing, filtration, Fill&Finish, lyophilization), process modelization, digital tools + **Education** **:** Biochemistry, chemistry, pharmaceutical engineering or related degree, PhD + **Languages** **:** French & English **Pursue** **_Progress_** **.** **Discover** **_Extraordinary_** **.** Progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. You can be one of those people. Chasing change, embracing new ideas and exploring all the opportunities we have to offer. Let’s pursue progress. And let’s discover extraordinary together. At Sanofi, we provide equal opportunities to all regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! **\#LI-FRA** \#mRNA **Pursue** **_progress_** **, discover** **_extraordinary_** Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) ! Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo) As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)