The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).
Please, check out our Recruitment Policy
The role
We are recruiting a researcher with advanced experience in single-cell methods to to benchmark and develop novel single-cell technologies. The project will support the Biodiversity Cell Atlas initiative and is funded by the Moore Foundation. The objective is to find robust methodologies to profile single-cell transcriptomes in non-model species across the Tree of Life. Therefore, this research requires of a advanced understanding of these different single-cell sample processing methods and single-cell genomics methodologies in order to adjust them to non-model species. The candidate will be a part of a coordinated team of molecular biologists and bioinformaticians.
About the team/ lab/ department
Our group studies genome regulation from an evolutionary systems perspective. In particular, we are interested in deciphering the evolutionary dynamics of animal cell type programs and in reconstructing the emergence of genome regulatory mechanisms linked to cell type differentiation (from transcription factor binding through chromatin states to the physical architecture of the genome). To this end, we apply advanced single-cell genomics, phylogenetic methods, and chromatin experimental methods to dissect and compare cell types across phylogenetically diverse organisms.
For further information you can directly email arnau.sebe@crg.eu
You can also consult our website: www.sebepedroslab.org
Whom would we like to hire?
Professional experience
Must Have
Experience in single-cell genomics protocols (e.g. scRNAseq, scATACseq)
Extensive expertise in molecular biology, particularly DNA/RNA biology
Desirable but not required/ Nice to have
Experience in operating liquid-handling robots (e.g. Agilent Bravo)
Experience in non-commercial single-cell RNA-seq methods (sciRNA-seq3, inDrops, etc.)
Experience in diverse nuclei isolation methods, particularly for challenging tissues
Experience in Nanopora long-read sequencing
Education and training
A bachelor/master's degree in biology/biochemistry (or related disciplines) or a lab technician qualification
Good understanding of different functional genomics methodologies
Languages
English fluency
Technical skills
Hands-on experience in genomics workflows (e.g. library preparation)
Hands-on experience in scRNA-seq protocols
Hands-on experience in basic molecular biology (e.g. DNA/RNA purification, cloning, protein protocols)
Competences
Highly developed organization and coordination skills
Dedication, motivation, and rigor in scientific pursuits
Capacity to work as part of a highly integrated team
The Offer – Working Conditions
Contract duration: Technical and scientific activities contract linke to the project (estimated duration 15/10/2026 with possibility of renewal)
Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
Target start date: April/May 2025
We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.
We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.
The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
Application Procedure
All applications must include:
A motivation letter addressed to Dr Arnau Sebe-Pedros
A complete CV including contact details.
Contact details of two referees.
All applications must be addressed to Dr. Arnau Sebe-Pedros and be submitted online through the "Apply" button below.
Selection Process
Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.
Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.
Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.
Deadline: Please submit your application by March 13, 2025