Senior Scientist (Bandopadhayay and Beroukhim Labs)
The Bandopadhayay Lab (www.bandolab.org) and Beroukhim Lab (www.beroukhimlab.org) at DFCI (with co-affiliations with Boston Children’s Hospital and the Broad Institute) are jointly seeking a Senior Research Scientist to spearhead multi-disciplinary efforts to identify and characterize novel therapeutic approaches for children diagnosed with pediatric gliomas. We apply cutting-edge genomic technologies to identify drivers of childhood cancers, identify strategies to target these and to determine mechanisms of resistance to current and novel treatments. The aim of these efforts is to perform translational research to develop new therapies to improve outcomes of children diagnosed with these tumors. The work will be highly translational and span efforts functional genomic methodologies to determine oncogenic mechanisms and identify new dependencies, studies to evaluate efficacy of small-molecule inhibitors, preparation of single-cell/single-nuclei libraries for next-generation sequencing, and studies to characterize mechanisms of glioma formation, and resistance of brain tumors to therapeutic strategies.
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
ResponsibilitiesThe ideal candidate will be passionate about developing a career of scientific discovery, a team player, enthusiastic about translational research to help improve patient outcomes, and highly self-motivated. They will coordinate research efforts across multiple projects in within our labs. There will be opportunities to help lead independent scientific projects and learn, assist in preparation of grants and to contribute to computational methods of analysis of large genomic datasets.
QualificationsRequired Education, Experience, and Skills:
PhD or MD/PhD degree in molecular biology, cellular biology, cancer biology, computational/computer science or related discipline. Candidates with MDs and significant research experience are also invited to applyEnthusiastic, team player, innovative and analytical thinker, and self-motivated individual.Experience with high throughput genetic perturbation approaches include CRISPR-cas9 assays in 3D organoids and neurospheres.Cell culture of brain tumor neurospheres, including drug sensitivity assaysProven track record of collaboration across teamsExcellent written and oral communication skillsExcellent mentorship skillsCandidate should have an outstanding academic and professional track recordApplicants are required to provide three referees at the time of application.
A minimum three-year availability is required.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEOC Poster
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