Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.

The Position

This Opportunity:

Lead a multidisciplinary team of drug discovery scientists to invent future medicines treating metabolic diseases.  Responsibilities may include planning and independently completing in vitro/in vivo experiments to support preclinical characterization and evaluation of targets/pathways that regulate body weight/composition, muscle mass, energy balance, and glucose homeostasis. Proven expertise in building disease-relevant cellular assays for metabolic disorders using immortalized and/or primary human and animal cells, including co-cultures and/or organoid culture systems.Perform molecular and biochemical assessments on ex vivo samples in collaboration with colleagues in other departments.Demonstrated ability to achieve results in a matrix organization.Requirement for accurate record keeping, independent data analysis, and reporting of data in written and oral formats.  Exceptional attention to detail with excellent written and verbal communication skills to clearly articulate complex concepts at all levels of the organization.

Desired:

A background in the biology and physiology of energy balance regulation and metabolic diseases.Experience with in vitro, ex vivo metabolic function assays to assess insulin sensitivity, glucose and lipid metabolism, mitochondrial function in cells or tissues.   Preferred experience includes: In vitro/in vivo pharmacology and experience working with metabolic relevant cell types and ex vivo system (adipocytes, skeletal/cardiac myocytes, islets/pancreatic beta cells, isolated muscle).   

Qualifications

PhD with a focus on metabolism, physiology, biology or related field.Work experience on drug discovery teams in metabolism discovery, preferably with a focus on metabolism in pharmaceutical industry settings is highly desired.Expertise in in vivo workflows, experimental design, execution, data analysis and interpretation.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche is an Equal Opportunity Employer.