San Diego, California, USA
15 days ago
Sr. Advisor - Analytical Chemistry - Discovery Chemistry Research & Technologies

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location.  The anticipated wage for this position is

$133,500 - $217,800

The Discovery Chemistry Research & Technologies organization within Lilly Research Laboratories (LRL) is seeking an Analytical Purification Scientist with expertise in supercritical fluid, normal and reverse phase chromatography to join our analytical team which is an integral part of the Medicinal Chemistry group located at Lilly Biotechnology Center, San Diego, CA.

 

The ideal candidate will:

Always keep safety as the top priority, striving to maintain a proactive safety culture.

Work across all areas of achiral and chiral purification modes including normal phase, reverse phase, and SFC, crude sample analysis, method selection/optimization, and material quality control.

Use their scientific knowledge and experience of various analytical techniques to solve diverse problems, develop purification methods, evaluate and/or implement new analytical technologies/methods and influence purification strategy at project, team, and departmental levels.

Have a strong collaboration-focused mentality to ensure portfolio project teams can rapidly iterate through design cycles.

Work in close collaboration with internal/external partners to ensure a strong relationship and rapid delivery of quality results in a format customized to meet their specific needs

Work to support and enhance analytical and small scale-preparative purification capabilities for high throughput chemistry experimentation and library synthesis

Be responsible for purification instruments, providing basic troubleshooting and partnering with groups for support.

Mentor and develop scientific staff. Ensure continued technical and professional growth of group members, encourage efforts towards excellence and knowledge sharing.

Actively engage in the external environment and the ability to recognize and apply external innovation across the Lilly portfolio.

Strong attention to detail and the ability to manage several projects simultaneously.

Contribute to Lilly Research Lab-wide initiatives embracing diversity of thought, background, and experience to deliver creative solutions in the face of ambiguity.

Enthusiastic and self-motivated, with excellent communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery

Demonstrate strong written and verbal communication skills to represent both the technical aspects and business-related implications of your work

 

Minimum Qualifications:   

Ph.D. in analytical chemistry, or a closely related field with 2+ years of experience in the pharmaceutical industry, or alternatively a B.S./M.S. in chemistry with 10+ years of experience in the pharmaceutical industry.

Proven hands-on experience in analysis and purification of small molecules and/or peptides by reverse phase (U)HPLC and SFC, in mass spectrometry, and experience in organic and medicinal chemistry.

Extensive theoretical knowledge of (U)HPLC and SFC chromatography and method development.

Proven hands-on experience running and interpreting data from (U)HPLCMS, SFCMS and UPHLC-TOFMS instruments.

 

Additional Desired Skills:

Experience with instrument maintenance.

Proven hands-on experience with analytical and preparative Waters, Agilent and/or Shimadzu(U)HPLC and SFC systems.

Experience with Waters (U)HPLC-qTOF instrumentation.

Experience running Bruker NMR spectrometers and interpreting 1D and 2D data.

Familiarity with variety of assays such as stability, racemization or forced degradation.

Experience with programming, automation and data management.

Experience with a variety of sample drying equipment, such as Genevac HT and Biotage V10 evaporators, and lyophilizers.

Learning agility and demonstrated ability to apply technical knowledge to improve the understanding of chemical systems or improve analytical techniques.

Demonstrated ability to balance multiple activities, prioritize evolving project needs, and handle ambiguity.

Enthusiastic and self-motivated, with the communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal deliver.

Excellent English communication skills (verbal and written).

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

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