If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this tip sheet.

The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Senior Research Associate 3 to work at the UHealth Medical Campus in Miami, FL.

CORE JOB SUMMARY                                                                                                                                                                                    

The Senior Research Associate 3 conducts highly specialized and complex research in support of the division’s research goals and objectives and assumes responsibility for the successful operations of the laboratory. The incumbent also supervises the activities of all laboratory staff and users and serves as subject matter expert and mentor to less experienced staff.

CORE JOB FUNCTIONS                                                                                                                                                  

Contributes to basic and applied research activities by collecting and analyzing data.

Understands and interprets research protocols and procedures.

Maintains an overview of relevant research findings.

Ensures all research is undertaken according to good research practice.

Designs, evaluates, and implements methods and protocols for assigned research projects.

Recommends purchase of new equipment for research projects.

Writes scientific articles and manuscripts for publication and presentation.

Oversees and ensures the safe handling of radioactive and hazardous materials.

Prepares analytical reports relative to research data.

Adheres to University and unit-level policies and procedures and safeguards University assets.

This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.

CORE QUALIFICATIONS                                                                                                                                                

Education:

Master’s Degree in relevant field required

Experience:

Minimum 5 years of relevant experience

Knowledge, Skills and Attitudes:

Skill in collecting, organizing, and analyzing data.

Ability to recognize, analyze, and solve a variety of problems.

Ability to exercise sound judgment in making critical decisions.

Department Specific Functions

The Sylvester Comprehensive Cancer Center is currently seeking a Microinjections - Senior Research Associate 3 who will join the Cancer Modeling Shared Resource. This translational Facility provides qualified, cost effective and state-of-the art services to foster cancer research advancements and accelerate the discovery of tailored antitumor therapies. We are seeking a dynamic individual who would like to participate in the creation and development of new service lines in a busy and fast-paced environment, mainly focused on the implementation of advanced techniques and technologies to produce and manipulate customized genetically engineered rodents. He or she will perform a broad range of tasks related to generation of genetically modified mice including microinjection of fertilized oocytes, microinjection and electroporation of zygotes, cryopreservation of embryos/sperm and reanimation of mouse strains, molecular biology, and mouse reproductive physiology methods. This person will directly assist the Director in running and implementing new services for the generation of transgenic, knock-out, knock-in and gene-edited mice, as well as developing and adapting state-of-the-art editing technologies to support researchers in the field of transgenesis and functional genomics. The successful candidate will also develop, implement, and update the procedures required to accomplish research goals and preclinical mouse model-related service provision under the direction of Dr. Bilbao.

The following job description reflects additional support that this position must provide.  Specific responsibilities of the position include and are not limited to:

Design, evaluate, and implement methods and protocols related to generation of transgenic and gene-edited mice and rats by zygote electroporation and pronuclear or cytoplasmic injection of DNA and CRISPR gRNA/cas9; and gene targeting by electroporation and injection of ES/iPS cells into blastocysts for the generation of chimeric mice. Design, evaluate, and implement methods and protocols related to preservation and reproductive support of novel mouse and rat lines generated, including embryo cryopreservation, sperm cryopreservation, in vitro fertilization, and rederivation. Responsible for embryo handling, embryo transfer and other relevant surgical procedures. Assist with the maintenance of the animal colonies, hormone injections for superovulation of mice and rats, tail biopsies, surgical vasectomies, and general lab maintenance. Prepare reagents to meet the demands of multiple research projects that will require flexible work hours working in concert with project scientists while adhering to quality control procedures for ensuring consistency of experimental outcomes. Understands nucleic acid chemistry, recombinant DNA manipulations, and gene transfer protocols, interprets experimental outcomes, and elaborates solutions to technical problems encountered while developing and implementing in transgenic-related services. Accurate and reliable record keeping including database management, batch records, notebooks, and all pertinent documentation. Analyze research data and prepare reports for the provision of transgenic and gene editing services. Work with the director and the team to develop, adapt and implement new services and state-of-the-art technologies to address scientific problems. Maintain cutting-edge technical knowledge of the transgenic field including major advances and emerging trends. Manage email communications and maintain internal documentation. Adhere to University and unit-level policies and procedures; safeguard University assets; participate in University/outside educational training as required. Perform other duties as requested.

Department Specific Qualifications                                                                                                                        

Experience:

The successful candidate must have a minimum of five years of research experience performing the routine as well as the specialized technical procedures mentioned above. Experience with animal handling, ES cell culture and genotyping techniques is preferred.

Knowledge, Skills and Attitudes:

Proactively helpful in all aspects of the job, whether it involves communication, training, reporting, or project management.

Mechanical ability and dexterity when performing the different lab and animal-related techniques.

Ability to understand reproductive and mouse biology.

Skill in completing assignments accurately and with attention to detail.

Ability to understand and follow specific instructions and procedures.

Excellent computer skills and proficiency with general and specialized data analysis software and databases is required.

Knowledge of the use and maintenance of laboratory facilities and/or specialized equipment.

Knowledge of lab procedures, general laboratory operations and/or procedures, as well as knowledge of supplies, equipment, and/or services ordering.

Self-motivated individual with a strong desire to learn.

Exceptional critical thinking and strong analytical, problem solving, and troubleshooting skills.

Excellent interpersonal and communication skills. He or she is expected to interact with a variety of staff (facility team, users, and other related facilities) in a professional, polite, and positive attitude.

Excellent English (both verbal and written) required.

Ability to shift focus between multiple projects, organize and prioritize work under pressure while meeting deadlines.

Excellent time-management skills.

Ability to work evenings, nights, and weekends as necessary.

Commitment to the University’s core values.

Ability to work independently and in a collaborative environment.

Ability to work in an interdisciplinary team under the direction of the Director of the Facility.

Ability to perform other duties as assigned.

#LI-YC1

The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.

UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.

The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information.

Job Status:

Employee Type:

Pay Grade: