Chicago, IL, USA
17 days ago
Sr. Staff Scientist

Department

BSD BMB - Perozo Lab


About the Department

The Center for Mechanical Excitability (CME) is dedicated to the study of the mechanobiome, the biological construct where forces are sensed, transduced, and exerted as part of a broad range of processes, both physiological and pathophysiological. Our approach covers a range of biological mechanisms both at the mesoscale and the nanoscale. We use an advanced toolkit that includes: biochemistry, biophysics, cell and molecular biology, structural biology and imaging, as well as AI-driven computational modeling and bioinformatics; all within the context of evolutionary biology
The Department of Biochemistry and Molecular Biology (BMB) studies how biomolecules function and interact to drive the complex, diverse, and adaptive behaviors of living systems. Our focus is on biological mechanisms described at the molecular level. We are highly collaborative and often employ multiple approaches to address otherwise intractable questions. We have particular strengths in membrane proteins and RNA biochemistry and are pioneers in all areas of biophysics, structural biology, biochemistry, and protein engineering and design. https://biochem.uchicago.edu/.

This at-will position is wholly or partially funded by contractual grant funding which is renewed under provisions set by the grantor of the contract. Employment will be contingent upon the continued receipt of these grant funds and satisfactory job performance.


Job Summary

The Sr. Staff Scientist will lead a research program focused on genetic modifications in cnidarians (jellyfish, sea anemones, corals) with the express goal of developing specifically tagged-in genetic lines of the following species: Clytia haemispherica, Hydra vulgaris and Nematostella vectrensis.

Responsibilities

Serves as a resource for collecting data and performing analysis. Facilitates and promotes a research project by providing scientific or intellectual information.

Develops laboratory protocols and training on new techniques. Manage, analyze and make recommendations on complex data sets for research.

Creates first drafts for scientific writing and publications, including protocols and grants.

Trains and mentors laboratory personnel.

Performs other related work as needed.


Minimum Qualifications

Education:

Minimum requirements include a PhD in related field.


Work Experience:

Minimum requirements include knowledge and skills developed through 5-7 years of work experience in a related job discipline.


Certifications:

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Preferred Qualifications

Experience:

Experience in the genetic manipulation of invertebrate (cnidarian) model systems, and a general understanding of membrane protein biochemistry.

Experience with the following:

Egg and embryo nucleic acid injections.

Gene knock-downs by RNAi methods.

Development of knock-in line using CRISPR/Cas9 methods.

In-situ hybridization.

Behavioral analyses (Prey killing assays).

Fluorescence imaging.

Cell fractionation.

Experience in bioinformatics.

Working Conditions

Wet Lab Environment.

Weekend/Evening Hours: As Needed.

Application Documents

Resume (required)

Cover Letter (preferred)


When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application.


Job Family

Research


Role Impact

Individual Contributor


Scheduled Weekly Hours

40


Drug Test Required
 

No


Health Screen Required
 

No


Motor Vehicle Record Inquiry Required
 

No


Pay Rate Type

Salary


FLSA Status

Exempt


Pay Range

$64,000.00 - $92,000.00

The included pay rate or range represents the University’s good faith estimate of the possible compensation offer for this role at the time of posting.


Benefits Eligible

Yes

The University of Chicago offers a wide range of benefits programs and resources for eligible employees, including health, retirement, and paid time off. Information about the benefit offerings can be found in the Benefits Guidebook.


Posting Statement
 

The University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender, gender identity, national or ethnic origin, age, status as an individual with a disability, military or veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination.

 

Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form.

 

We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange.

 

All offers of employment are contingent upon a background check that includes a review of conviction history.  A conviction does not automatically preclude University employment.  Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position.

 

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