**Join Amgen’s Mission of Serving Patients** At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. **Synthetics Supply DS & DP - Engineer** **What you will do** Let’s do this! Let’s change the world! Amgen’s Synthetic Manufacturing and Clinical Supply Organization is seeking a highly motivated Engineer to join our diverse team of engineers, scientists, and technicians in Thousand Oaks, CA. The applicant will be responsible for manufacturing support activities in our Synthetic Drug Substance Scale-Up Facility and Drug Product Formulation Development Lab facility. The candidate will work in a highly collaborative team environment and be responsible for both non-GMP and GMP manufacturing activities to support of our early phase clinical pipeline of synthetic drug substance and drug products. **Job Responsibilities:** + Hands-on cleaning, sanitization, and setup of equipment parts + Support manufacturing process readiness activities + Review facility and equipment documentation (equipment/room logbooks) + Maintenance of Raw Materials & Consumables Inventory + Supporting day to day operational needs of the facility + Dispensing and handling of high hazardous raw materials + Operating machinery and tools while complying to all safety protocols and operational standards + Support batch records for use in GLP/GMP campaigns and planning manufacturing timelines + Identify, recommend, and implement improvements related to routine functions + Collaborate in a multidisciplinary team with process development chemists, engineers, analysts, and facility staff The candidate will collaborate in multi-disciplinary teams with Process Development scientists, engineers, EH&S, Quality, F&E, maintenance, and other supporting functions. **What we expect of you** We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is an individual with these qualifications. **Basic Qualifications:** + High school diploma / GED and 8 years of Engineering experience OR + Associate’s degree and 6 years of Engineering experience OR + Bachelor’s degree and 2 years of Engineering experience OR + Master’s degree **Preferred Qualifications:** + Bachelor’s degree in life Sciences, Chemistry, or Engineering related fields + Extensive knowledge of safe chemical handling techniques, including weighing, dispensing, and packaging of chemical, drug substance intermediates, and APIs + Experience with laboratory automation including temperature control and data logging platforms such as Delta V & Pl vision + Ability to adhere to current Good Manufacturing Practices cGMPs and follow Standard Operating Procedures SOPs. + Understanding of unit operations for the manufacture of synthetic drug substance (i.e. weighing and dispensing, reactor charging, reactor and filter operations and other common unit operations) and for drug product (i.e. granulation, roller compaction, drying, milling, blending, compression, encapsulation and film coating) + Strong technical skills for troubleshooting & process improvement + Proficiency in using PPE, including PAPR and breathing air suits. + Ability to work with Microsoft Office, Excel, and PowerPoint + Excellent verbal and written communication skills + Strong interpersonal skills and a proactive leadership mindset **What you can expect of us** As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: + A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts + A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan + Stock-based long-term incentives + Award-winning time-off plans + Flexible work models, including remote and hybrid work arrangements, where possible **Apply now** **for a career that defies imagination** Objects in your future are closer than they appear. Join us. **careers.amgen.com** In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.